Literature DB >> 16919922

[Apnea of prematurity: risk factors and ambulatory treatment with caffeine citrate].

S Ducrocq1, V Biran-Mucignat, P-Y Boelle, F Lebas, J-J Baudon, F Gold.   

Abstract

INTRODUCTION: Apnea of prematurity develop during the first days of life and usually resolve by the time the infant reaches 36-37 weeks postmenstrual age. In a few cases, they persist beyond term, especially in infants delivered at the youngest gestational ages (24-28 GA), and require specific care. In our unit, those preterm babies are discharged home with caffeine citrate treatment. Discontinuing the treatment is performed in hospital when they achieve a postmenstrual age of at least 42 weeks.
OBJECTIVE: To identify predictive factors of persistent apnea in preterm babies.
MATERIAL AND METHODS: Retrospective study comparing a population of 41 preterm infants discharged with treatment to 123 preterm babies discharged without treatment to identify predictors of persistent apnea.
RESULTS: Factors significantly associated were: birth weight<1500 g, initial hypotension, gastroesophageal reflux, need for continuous positive airway pressure and multiparity. At home, no infant died and no adverse effect was reported by parents.
CONCLUSION: Persistent apnea can be responsible for prolonged hospitalization. Risk factors can be identified in some children. Discharging with treatment can be an alternative to their hospitalization.

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Year:  2006        PMID: 16919922     DOI: 10.1016/j.arcped.2006.06.016

Source DB:  PubMed          Journal:  Arch Pediatr        ISSN: 0929-693X            Impact factor:   1.180


  3 in total

1.  Non-Rotavirus infection causing apnea in a neonate.

Authors:  Majeeda Kamaluddeen; Abhay Lodha; Albert Akierman
Journal:  Indian J Pediatr       Date:  2009-11-12       Impact factor: 1.967

Review 2.  Apnea of prematurity: from cause to treatment.

Authors:  Jing Zhao; Fernando Gonzalez; Dezhi Mu
Journal:  Eur J Pediatr       Date:  2011-02-08       Impact factor: 3.183

3.  Caffeine versus aminophylline in combination with oxygen therapy for apnea of prematurity: A retrospective cohort study.

Authors:  Cheng-Yun Zhang; Dong-Jie Liu; Shao-Dong Hua; Shan Guo; Xiao-Yan Li; Bing Zhang; Li-Hua An
Journal:  Exp Ther Med       Date:  2020-09-03       Impact factor: 2.447

  3 in total

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