OBJECTIVE: We investigated the prevalence of asymptomatic pyuria (ASP) in diabetic patients and compared the Sysmex UF-100 with Fuchs-Rosenthal hemacytometer. DESIGN AND METHODS: ASP prevalence was investigated in 227 diabetic patients. Imprecision, accuracy and correlation of UF-100 with hemacytometer in measuring leukocyte counts were determined. RESULTS: Diabetic women and men had significantly higher ASP prevalence than non-diabetic women (21.4 vs. 8.7%) and men (12.2 vs. 3.4%). Disease duration and HbA(1C) levels were similar in diabetic patients with and without ASP. UF-100 and hemacytometer readings correlated significantly (r=0.88) without a significant bias. Within-run coefficients of variations for UF-100 (8.14, 6.35 and 12.18%) and hemacytometer (5.14, 5.18 and 8.03%) did not differ significantly. CONCLUSIONS: Prevalence of ASP is increased in diabetic patients and not affected by duration of disease or control of hyperglycemia. UF-100 seemed to be a reliable, precise and accurate system to determine pyuria.
OBJECTIVE: We investigated the prevalence of asymptomatic pyuria (ASP) in diabeticpatients and compared the Sysmex UF-100 with Fuchs-Rosenthal hemacytometer. DESIGN AND METHODS: ASP prevalence was investigated in 227 diabeticpatients. Imprecision, accuracy and correlation of UF-100 with hemacytometer in measuring leukocyte counts were determined. RESULTS:Diabeticwomen and men had significantly higher ASP prevalence than non-diabeticwomen (21.4 vs. 8.7%) and men (12.2 vs. 3.4%). Disease duration and HbA(1C) levels were similar in diabeticpatients with and without ASP. UF-100 and hemacytometer readings correlated significantly (r=0.88) without a significant bias. Within-run coefficients of variations for UF-100 (8.14, 6.35 and 12.18%) and hemacytometer (5.14, 5.18 and 8.03%) did not differ significantly. CONCLUSIONS: Prevalence of ASP is increased in diabeticpatients and not affected by duration of disease or control of hyperglycemia. UF-100 seemed to be a reliable, precise and accurate system to determine pyuria.
Authors: Sabine K Schuh; Ruth Seidenberg; Spyridon Arampatzis; Alexander B Leichtle; Wolf E Hautz; Aristomenis K Exadaktylos; Clyde B Schechter; Martin Müller Journal: Dis Markers Date: 2019-03-03 Impact factor: 3.434