Literature DB >> 16919614

Structure, function and regulation of carboxylesterases.

Tetsuo Satoh1, Masakiyo Hosokawa.   

Abstract

This review covers current developments in molecular-based studies of the structure and function of carboxylesterases. To allay the confusion of the classic classification of carboxylesterase isozymes, we have proposed a novel nomenclature and classification of mammalian carboxylesterases on the basis of molecular properties. In addition, mechanisms of regulation of gene expression of carboxylesterases by xenobiotics and involvement of carboxylesterase in drug metabolism and enzyme induction are also described.

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Year:  2006        PMID： 16919614     DOI： 10.1016/j.cbi.2006.07.001

Source DB:  PubMed          Journal:  Chem Biol Interact        ISSN： 0009-2797            Impact factor:   5.192


  102 in total

1.  Selective esterase-ester pair for targeting small molecules with cellular specificity.

Authors:  Lin Tian; Yunlei Yang; Laura M Wysocki; Alma C Arnold; Amy Hu; Balaji Ravichandran; Scott M Sternson; Loren L Looger; Luke D Lavis
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-12       Impact factor: 11.205

2.  Mammalian carboxylesterase 3: comparative genomics and proteomics.

Authors:  Roger S Holmes; Laura A Cox; John L VandeBerg
Journal:  Genetica       Date:  2010-04-28       Impact factor: 1.082

Review 3.  Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.

Authors:  Antonia H Tolson; Hongbing Wang
Journal:  Adv Drug Deliv Rev       Date:  2010-08-17       Impact factor: 15.470

4.  Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds.

Authors:  Karen L Jansen; Toby B Cole; Sarah S Park; Clement E Furlong; Lucio G Costa
Journal:  Toxicol Appl Pharmacol       Date:  2009-02-09       Impact factor: 4.219

Review 5.  The role of human carboxylesterases in drug metabolism: have we overlooked their importance?

Authors:  S Casey Laizure; Vanessa Herring; Zheyi Hu; Kevin Witbrodt; Robert B Parker
Journal:  Pharmacotherapy       Date:  2013-02       Impact factor: 4.705

6.  Effect of carboxylesterase 1 c.428G > A single nucleotide variation on the pharmacokinetics of quinapril and enalapril.

Authors:  E Katriina Tarkiainen; Aleksi Tornio; Mikko T Holmberg; Terhi Launiainen; Pertti J Neuvonen; Janne T Backman; Mikko Niemi
Journal:  Br J Clin Pharmacol       Date:  2015-06-11       Impact factor: 4.335

7.  Supporting the recommended paediatric dosing regimen for rufinamide in Lennox-Gastaut syndrome using clinical trial simulation.

Authors:  M Marchand; E Fuseau; D J Critchley
Journal:  J Pharmacokinet Pharmacodyn       Date:  2010-02       Impact factor: 2.745

8.  Carboxylate Surrogates Enhance the Antimycobacterial Activity of UDP-Galactopyranose Mutase Probes.

Authors:  Valerie J Winton; Claudia Aldrich; Laura L Kiessling
Journal:  ACS Infect Dis       Date:  2016-06-29       Impact factor: 5.084

9.  Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin.

Authors:  Dongfang Yang; Robin E Pearce; Xiliang Wang; Roger Gaedigk; Yu-Jui Yvonne Wan; Bingfang Yan
Journal:  Biochem Pharmacol       Date:  2008-10-15       Impact factor: 5.858

10.  Baboon carboxylesterases 1 and 2: sequences, structures and phylogenetic relationships with human and other primate carboxylesterases.

Authors:  Roger S Holmes; Jeremy P Glenn; John L VandeBerg; Laura A Cox
Journal:  J Med Primatol       Date:  2009-02       Impact factor: 0.667
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