| Literature DB >> 16919457 |
Jinyou Xu1, Lan Wei, Robert J Mathvink, Scott D Edmondson, George J Eiermann, Huaibing He, Joseph F Leone, Barbara Leiting, Kathryn A Lyons, Frank Marsilio, Reshma A Patel, Sangita B Patel, Aleksandr Petrov, Giovanna Scapin, Joseph K Wu, Nancy A Thornberry, Ann E Weber.
Abstract
A novel series of oxadiazole based amides have been shown to be potent DPP-4 inhibitors. The optimized compound 43 exhibited excellent selectivity over a variety of DPP-4 homologs.Entities:
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Year: 2006 PMID： 16919457 DOI： 10.1016/j.bmcl.2006.07.061
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823