| Literature DB >> 1691903 |
Abstract
Thrombospondin is a large, multifunctional glycoprotein released from activated platelets and secreted by growing cells. It binds to components of the cell surface and extracellular milieu. Thrombospondin probably modulates a number of processes, including aggregation of platelets, formation and lysis of fibrin, adhesion and migration of cells, and progression of cells through the growth cycle. Studies relating thrombospondin to disease processes are just beginning.Mesh：
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Year: 1990 PMID： 1691903 DOI： 10.1146/annurev.me.41.020190.000505
Source DB: PubMed Journal: Annu Rev Med ISSN： 0066-4219 Impact factor: 13.739