Literature DB >> 16918226

Intrathecal baclofen in the treatment of adult spasticity.

Joseph C Hsieh1, Richard D Penn.   

Abstract

Medical management of adult spasticity, a condition of increased muscle tone and deep tendon reflexes, is often challenging and complex. Oral medications such as baclofen often have unacceptable supraspinal side effects at effective doses. Intrathecal baclofen delivered by an implanted catheter and pump system provides good relief of spasticity while overcoming these limitations. In this paper the authors survey the use of oral and intrathecal baclofen therapy, detail the surgical process, and explain the risks and benefits of the procedure.

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Year:  2006        PMID: 16918226     DOI: 10.3171/foc.2006.21.2.6

Source DB:  PubMed          Journal:  Neurosurg Focus        ISSN: 1092-0684            Impact factor:   4.047


  7 in total

Review 1.  Neuraxial drug administration: a review of treatment options for anaesthesia and analgesia.

Authors:  Stephan A Schug; David Saunders; Irina Kurowski; Michael J Paech
Journal:  CNS Drugs       Date:  2006       Impact factor: 5.749

2.  Intrathecal baclofen for spasticity management: a comparative analysis of spasticity of spinal vs cortical origin.

Authors:  April Saval; Anthony E Chiodo
Journal:  J Spinal Cord Med       Date:  2010       Impact factor: 1.985

3.  Impairment of GABAB receptor dimer by endogenous 14-3-3ζ in chronic pain conditions.

Authors:  Sophie Laffray; Rabia Bouali-Benazzouz; Marie-Amélie Papon; Alexandre Favereaux; Yang Jiang; Tina Holm; Corentin Spriet; Pascal Desbarats; Pascal Fossat; Yves Le Feuvre; Marion Decossas; Laurent Héliot; Ulo Langel; Frédéric Nagy; Marc Landry
Journal:  EMBO J       Date:  2012-06-12       Impact factor: 11.598

4.  Intrathecal baclofen overdose mimicking brainstem death during deep brain stimulation surgery for pain.

Authors:  A Alamri; A Mostofi; T Aziz; E Pereira
Journal:  Ann R Coll Surg Engl       Date:  2022-05-26       Impact factor: 1.951

5.  CNS penetration of intrathecal-lumbar idursulfase in the monkey, dog and mouse: implications for neurological outcomes of lysosomal storage disorder.

Authors:  Pericles Calias; Mikhail Papisov; Jing Pan; Nancy Savioli; Vasily Belov; Yan Huang; Jason Lotterhand; Mary Alessandrini; Nan Liu; Alan J Fischman; Jan L Powell; Michael W Heartlein
Journal:  PLoS One       Date:  2012-01-18       Impact factor: 3.240

6.  Intrathecal baclofen therapy for spasticity: A compliance-based study to indicate effectiveness.

Authors:  Hussam Abou Al-Shaar; Ahmed Alkhani
Journal:  Surg Neurol Int       Date:  2016-08-02

7.  Effectiveness and safety of cervical catheter tip placement in intrathecal baclofen treatment of spasticity: A systematic review.

Authors:  Nora W Jacobs; Ellen M Maas; Marjolein Brusse-Keizer; Hans J S Rietman
Journal:  J Rehabil Med       Date:  2021-07-09       Impact factor: 2.912

  7 in total

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