Literature DB >> 16916774

Extracorporeal shock-wave lithotripsy monotherapy of partial staghorn calculi. Prognostic factors and long-term results.

Ahmed El-Assmy1, Ahmed R El-Nahas, Khaled Madbouly, Mohamed Abdel-Khalek, Mohamed E Abo-Elghar, Khaled Z Sheir.   

Abstract

OBJECTIVE: To define factors affecting the success and long-term outcome of extracorporeal shock-wave lithotripsy (ESWL) monotherapy of partial staghorn calculi.
MATERIAL AND METHODS: We retrospectively reviewed 92 patients with partial staghorn calculi who were treated with ESWL monotherapy. The outcome of the treatment was evaluated after 3 months. Long-term follow-up data (>24 months) were available for 49 patients. These data were further analyzed to determine long-term outcome.
RESULTS: At 3 months, the overall stone-free rate was 59.8%. Multiple ESWL sessions were required in 85.8% of patients. Stone surface area>500 mm2 was the only factor that significantly decreased the stone-free rate. Post-ESWL complications occurred in 12 patients (13%), among whom renal obstruction was observed in 10.8%. Secondary procedures were needed in 17 cases (18.4%). After a mean follow-up period of 7.5 years, the stone-free rate was 59.2% (29/49) and one-third of patients developed recurrence. In the long term, clinically insignificant residual fragments (CIRFs) passed spontaneously in 23% of patients, remained stable in 38.5% and became bigger in 38.5%. Regrowth of CIRFs was related to a history of stone recurrence. No patients showed deterioration of kidney function on the treated side and an improvement in pre-ESWL hydronephrosis was observed in 73.3% of patients.
CONCLUSIONS: ESWL is suitable for staghorn stones<or=500 mm2. In the long term, CIRFs became bigger and required secondary intervention in one-third of patients. A history of stone recurrence is a significant predictor of regrowth of CIRFs. ESWL provides long-term preservation of function of the treated kidneys; however, one-third of patients develop recurrence.

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Year:  2006        PMID: 16916774     DOI: 10.1080/00365590600743990

Source DB:  PubMed          Journal:  Scand J Urol Nephrol        ISSN: 0036-5599


  4 in total

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2.  Case Report: Successful Staged Ureteroscopic Treatment of a 5 cm Staghorn Renal Calculus.

Authors:  Joseph M Ciccone; J Clinton McCabe; Robert C Eyre
Journal:  Case Rep Urol       Date:  2012-02-25

Review 3.  Management of staghorn renal stones.

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Journal:  Ren Fail       Date:  2018-11       Impact factor: 2.606

Review 4.  Contemporary best practice in the management of staghorn calculi.

Authors:  Adam Sharbaugh; Tara Morgan Nikonow; Gregory Kunkel; Michelle Jo Semins
Journal:  Ther Adv Urol       Date:  2019-05-09
  4 in total

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