Literature DB >> 16916134

Rare cause of pleural nodularity: Splenosis.

Suat Gezer1, S S Erkmen Gülhan, Tamer Altinok, Yetkin Agaçkiran, A Irfan Tastepe.   

Abstract

Splenosis is a rare condition described as ectopic splenic tissue implantation generally after a splenic rupture. A 35-year-old male patient who had a history of splenectomy operation due to gunshot wound seven years ago was referred to our hospital with complaints, including exhaustion, sweating and shortness of breath. Thoracic computed tomography of the patient showed nodular pleural thickenings at the level of the left lower lobe, which proved to be unrelated with the presenting symptoms. The patient underwent a minithoracotomy for diagnosis and treatment. During the intraoperative observation, dark-colored, soft, multiple nodular lesions with a biggest size of 2 cm inside the visceral pleura over an area of 5 x 10 cm in dimension were observed. Also, a few tiny nodules in the lung parenchyma approximately 1-cm deep to the pleural nodules were palpated. The lesions were excised. The histopathological examination of the specimen showed splenic tissue in the lung parenchyma and pleura, so the lesions were accepted as splenosis. Pleuropulmonary splenosis, which develops generally after simultaneous rupture of the diaphragma and spleen, is a very rare condition. Most of the patients are asymptomatic and the lesions are detected accidentally. If the diagnosis can be made preoperatively, surgical excision is not needed.

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Year:  2006        PMID: 16916134      PMCID: PMC2569557     

Source DB:  PubMed          Journal:  J Natl Med Assoc        ISSN: 0027-9684            Impact factor:   1.798


  12 in total

1.  Thoracic splenosis 25 years after gunshot wound to the abdomen.

Authors:  J S Miller; A Nunez; R Espada
Journal:  J Trauma       Date:  2001-01

2.  Pleural nodularity in a patient with pyrexia of unknown origin.

Authors:  Peter B Wold; Michael A Farrell
Journal:  Chest       Date:  2002-08       Impact factor: 9.410

3.  An unusual cause of chest pain.

Authors:  Karthikeyan Gopal; Mark Trevor Jones; Susan Melanie Greaves
Journal:  Chest       Date:  2004-04       Impact factor: 9.410

4.  Thoracic splenosis presenting with hemoptysis.

Authors:  J F Cordier; J P Gamondes; P Marx; I Heinen; R Loire
Journal:  Chest       Date:  1992-08       Impact factor: 9.410

5.  Diagnosis of thoracic splenosis by tru-cut needle biopsy.

Authors:  J J Gaines; J H Crosby; M Vinayak Kamath
Journal:  Am Rev Respir Dis       Date:  1986-06

6.  Immunological function in post-traumatic splenosis.

Authors:  J M Hathaway; R A Harley; S Self; G Schiffman; G Virella
Journal:  Clin Immunol Immunopathol       Date:  1995-02

7.  Pulmonary parenchymal splenosis.

Authors:  R Sarda; I Sproat; D F Kurtycz; R Hafez
Journal:  Diagn Cytopathol       Date:  2001-05       Impact factor: 1.582

8.  The born-again spleen. Return of splenic function after splenectomy for trauma.

Authors:  H A Pearson; D Johnston; K A Smith; R J Touloukian
Journal:  N Engl J Med       Date:  1978-06-22       Impact factor: 91.245

Review 9.  Radionuclide imaging in thoracic splenosis and a review of the literature.

Authors:  Joseph N Yammine; Ahmad Yatim; Antoine Barbari
Journal:  Clin Nucl Med       Date:  2003-02       Impact factor: 7.794

10.  [Noninvasive diagnosis of posttraumatic thoracic splenosis].

Authors:  M Rubio Garay; J Belda Sanchís; M Iglesias Sentís; J M Gimferrer Garolera; M Catalán Biel; M A Callejas Pérez
Journal:  Arch Bronconeumol       Date:  2004-03       Impact factor: 4.872

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  6 in total

1.  If you suspect it, you can avoid thoracotomies.

Authors:  Khan Amir Maqbul; Berman Andrew
Journal:  J Natl Med Assoc       Date:  2007-01       Impact factor: 1.798

Review 2.  Thoracic splenosis: know it--avoid unnecessary investigations, interventions, and thoracotomy.

Authors:  Amir Maqbul Khan; Kamran Manzoor; Zeeshan Malik; Yesim Avsar; Avsar Yasim; Chang Shim
Journal:  Gen Thorac Cardiovasc Surg       Date:  2011-04-12

3.  Parenchymal thoracic splenosis: history and nuclear imaging without invasive procedures may provide diagnosis.

Authors:  Umer Feroze Malik; Mersadies R Martin; Rupal Patel; Ahmed Mahmoud
Journal:  J Clin Med Res       Date:  2010-08-18

4.  Symptomatic Intrathoracic Splenosis More than Forty Years After a Gunshot Injury.

Authors:  Adnan Khan; Sana Khan; Saran Pillai
Journal:  Cureus       Date:  2019-10-24

5.  Combined Intrathoracic and Subcutaneous Splenosis Discovered 51 Years after Abdominal Trauma.

Authors:  James Benjamin Gleason; Anas Hadeh; Maria Julia Diacovo; Jonathan Ryan Schroeder
Journal:  Case Rep Pulmonol       Date:  2015-07-08

6.  Intrathoracic splenosis - lesson learned: a case report.

Authors:  Lubomír Tulinský; Peter Ihnát; Marcel Mitták; Petra Guňková; Pavel Zonča
Journal:  J Cardiothorac Surg       Date:  2016-04-26       Impact factor: 1.637

  6 in total

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