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Literature DB >> 16915364

Systemic and brain metabolic dysfunction as a new paradigm for approaching Alzheimer's dementia.

Vincenzo Giordano¹, Gianfranco Peluso, Maurizio Iannuccelli, Paola Benatti, Raffaella Nicolai, Menotti Calvani.

Abstract

Since its definition Alzheimer's disease has been at the centre of consideration for neurologists, psychiatrists, and pathologists. With John P. Blass it has been disclosed a different approach Alzheimer's disease neurodegeneration understanding not only by the means of neurochemistry but also biochemistry opening new scenarios in the direction of a metabolic system degeneration. Nowadays, the understanding of the role of cholesterol, insulin, and adipokines among the others in Alzheimer's disease etiopathogenesis is clarifying approaches valuable not only in preventing the disease but also for its therapy.

Entities: Chemical Disease Gene

Mesh：

Substances：

Year: 2006 PMID： 16915364 DOI： 10.1007/s11064-006-9125-8

Source DB: PubMed Journal: Neurochem Res ISSN： 0364-3190 Impact factor: 3.996

172 in total

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17 in total

Review 1. Does the brain shrink as the waist expands?

Authors: Auriel A Willette; Dimitrios Kapogiannis
Journal: Ageing Res Rev Date: 2014-04-22 Impact factor: 10.895

Review 2. The therapeutic potential of metabolic hormones in the treatment of age-related cognitive decline and Alzheimer's disease.

Authors: John Grizzanti; Hyoung-Gon Lee; Antoni Camins; Merce Pallas; Gemma Casadesus
Journal: Nutr Res Date: 2016-11-08 Impact factor: 3.315

3. Biomarkers for insulin resistance and inflammation and the risk for all-cause dementia and alzheimer disease: results from the Framingham Heart Study.

Authors: Thomas M van Himbergen; Alexa S Beiser; Masumi Ai; Sudha Seshadri; Seiko Otokozawa; Rhoda Au; Nuntakorn Thongtang; Philip A Wolf; Ernst J Schaefer
Journal: Arch Neurol Date: 2012-05

4. Serum Adiponectin Levels, Neuroimaging, and Cognition in the Mayo Clinic Study of Aging.

Authors: Alexandra M V Wennberg; Deborah Gustafson; Clinton E Hagen; Rosebud O Roberts; David Knopman; Clifford Jack; Ronald C Petersen; Michelle M Mielke
Journal: J Alzheimers Dis Date: 2016-05-04 Impact factor: 4.472

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Authors: Antonio L Teixeira; Breno S Diniz; Alline C Campos; Aline S Miranda; Natalia P Rocha; Leda L Talib; Wagner F Gattaz; Orestes V Forlenza
Journal: Neuromolecular Med Date: 2012-09-28 Impact factor: 3.843

6. Adiponectin Attenuates Streptozotocin-Induced Tau Hyperphosphorylation and Cognitive Deficits by Rescuing PI3K/Akt/GSK-3β Pathway.

Authors: Zhi-Peng Xu; Guo-Sheng Gan; Yu-Min Liu; Jin-Song Xiao; Han-Xing Liu; Bin Mei; Jun-Jian Zhang
Journal: Neurochem Res Date: 2017-11-02 Impact factor: 3.996

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Authors: Leonid F Dmitriev
Journal: Neurochem Res Date: 2007-05-31 Impact factor: 3.996