Literature DB >> 16915233

Can open-source R&D reinvigorate drug research?

Bernard Munos1.   

Abstract

The low number of novel therapeutics approved by the US FDA in recent years continues to cause great concern about productivity and declining innovation. Can open-source drug research and development, using principles pioneered by the highly successful open-source software movement, help revive the industry?

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Year:  2006        PMID: 16915233     DOI: 10.1038/nrd2131

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


  21 in total

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2.  More medicines for neglected and emerging infectious diseases.

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Review 3.  Lessons from 60 years of pharmaceutical innovation.

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7.  Open Data, Open Source and Open Standards in chemistry: The Blue Obelisk five years on.

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Journal:  J Cheminform       Date:  2011-10-14       Impact factor: 5.514

8.  Common characteristics of open source software development and applicability for drug discovery: a systematic review.

Authors:  Christine Ardal; Annette Alstadsæter; John-Arne Røttingen
Journal:  Health Res Policy Syst       Date:  2011-09-28

9.  A kernel for open source drug discovery in tropical diseases.

Authors:  Leticia Ortí; Rodrigo J Carbajo; Ursula Pieper; Narayanan Eswar; Stephen M Maurer; Arti K Rai; Ginger Taylor; Matthew H Todd; Antonio Pineda-Lucena; Andrej Sali; Marc A Marti-Renom
Journal:  PLoS Negl Trop Dis       Date:  2009-04-21

10.  Distributed Drug Discovery, Part 1: linking academia and combinatorial chemistry to find drug leads for developing world diseases.

Authors:  William L Scott; Martin J O'Donnell
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