Literature DB >> 16914486

Acute coronary syndromes and their presentation in Asian and Caucasian patients in Britain.

Molly Teoh1, Susan Lalondrelle, Michael Roughton, Richard Grocott-Mason, Simon W Dubrey.   

Abstract

OBJECTIVE: To describe and compare demographics and symptom presentation in Asian and Caucasian patients with acute coronary syndromes.
DESIGN: Long-term prospective survey of symptom presentations in two racial groups.
SETTING: A London hospital. PARTICIPANTS: A consecutive series of patients admitted to hospital with acute coronary syndromes between November 2001 and November 2005. MAIN OUTCOME MEASURE: Comparison of demographics and location, character, intensity and symptom distribution at presentation between Asian and Caucasian patients.
RESULTS: Asian patients were younger than Caucasian patients (61 v 69 years, p<0.001) and more had diabetes (43% v 17%, p<0.001). Proportionally, more Asian patients had angina (51% v 37%, p<0.001), but more Caucasian patients had myocardial infarction (63% v 49%, p<0.001) and non-ST elevation infarcts (40% v 29%, p<0.001). Men reported smaller areas of discomfort than women. Asian patients more frequently reported discomfort over the rear of their upper bodies compared to Caucasian patients (46% v 25%, p<0.001) and radiation of discomfort to their arms and necks. A higher percentage of Asian than Caucasian patients demonstrated a "classical" location of symptoms (90% v 82%, p<0.001). Patients with diabetes were more likely to feel no discomfort. A higher percentage of Caucasian than Asian patients presented with "silent" events (13% v 6%, p>0.001), with age being a major determinant.
CONCLUSION: Asian patients were younger, more likely to be diabetic and tended to report a higher intensity of pain and over a greater area of their body, and more frequent discomfort over the rear of their upper thorax than Caucasian patients.

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Year:  2006        PMID: 16914486      PMCID: PMC1861382          DOI: 10.1136/hrt.2006.091900

Source DB:  PubMed          Journal:  Heart        ISSN: 1355-6037            Impact factor:   5.994


  28 in total

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