Literature DB >> 16912521

[Bone metastasis of gastric cancer].

Hideo Sudo1, Yu Takagi, So Katayanagi, Sumito Hoshino, Takeshi Suda, Yasuhiro Hibi, Kazushige Ito, Akihiko Tsutida, Tatsuya Aoki.   

Abstract

We evaluated 19 patients with bone metastasis after surgery for gastric cancer. In a number of cases, the located in the tumor was U and M region, of macroscopic 3, and the histological type was poorly-differentiated adenocarcinoma with high-grade of lymphatic invasion. The major symptom was lumbago and back pain. The serum AFP level was high in 73.7% of the cases, and LDH was high in 47.7%. The metastatic lesion was predominantly seen in the bone with red pulp such as lumbar and thoracic vertebra and rib. The median survival time was 189 days (range: 24-509) with a poor prognosis. However, newly developed anticancer drugs were very effective for some cases, indicating that such chemotherapy should be tried for cases with bone metastasis.

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Mesh:

Year:  2006        PMID: 16912521

Source DB:  PubMed          Journal:  Gan To Kagaku Ryoho        ISSN: 0385-0684


  6 in total

1.  Advanced or metastatic gastric cancer in elderly patients: clinicopathological, prognostic factors and treatments.

Authors:  Z Lu; M Lu; X Zhang; J Li; J Zhou; J Gong; J Gao; J Li; X Zhang; Y Li; L Shen
Journal:  Clin Transl Oncol       Date:  2012-10-02       Impact factor: 3.405

2.  Gastric phenotype signet-ring cell carcinoma of the stomach with multiple bone metastases effectively treated with sequential methotrexate and 5-fluorouracil.

Authors:  Tsutomu Mizoshita; Hiromi Kataoka; Eiji Kubota; Yasuyuki Okamoto; Takaya Shimura; Yoshinori Mori; Tsuneya Wada; Naotaka Ogasawara; Makoto Sasaki; Takeshi Kamiya; Takashi Joh
Journal:  Int J Clin Oncol       Date:  2008-08-15       Impact factor: 3.402

3.  Clinical significance of interleukin (IL)-6 in cancer metastasis to bone: potential of anti-IL-6 therapies.

Authors:  Ken Tawara; Julia T Oxford; Cheryl L Jorcyk
Journal:  Cancer Manag Res       Date:  2011-05-18       Impact factor: 3.989

4.  Bone metastasis from gastric cancer: the incidence, clinicopathological features, and influence on survival.

Authors:  Fatma Paksoy Turkoz; Mustafa Solak; Saadettin Kilickap; Arife Ulas; Onur Esbah; Berna Oksuzoglu; Suayib Yalcin
Journal:  J Gastric Cancer       Date:  2014-09-30       Impact factor: 3.720

5.  Long-term survival after gastrectomy and metastasectomy for gastric cancer with synchronous bone metastasis.

Authors:  Young Jin Choi; Dae Hoon Kim; Hye Suk Han; Joung-Ho Han; Seung-Myoung Son; Dong Soo Kim; Hyo Yung Yun
Journal:  World J Gastroenterol       Date:  2018-01-07       Impact factor: 5.742

6.  Individualized treatment for gastric cancer with rib metastasis: A case report.

Authors:  Yu Zhang; Zhen-Xing Zhang; Zeng-Xin Lu; Fang Liu; Geng-Yuan Hu; Feng Tao; Min-Feng Ye
Journal:  World J Gastrointest Surg       Date:  2020-12-27
  6 in total

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