BACKGROUND: The efficacy of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression has been assessed in a number of acute treatment trials during the last 10 years. Little is known about the long-term impact of the treatment on the disorder and its effectiveness when applied for repeated relapses of depression over time. METHOD: Nineteen patients who had previously responded to rTMS in clinical trials received treatment with rTMS for a total of 30 episodes of depressive relapse. RESULTS: Approximately 10 months elapsed between treatment episodes. The majority of patients achieved a significant improvement in each treatment course with significant improvements achieved in patients treated with both low-frequency right-sided rTMS and high-frequency left-sided rTMS. CONCLUSIONS: The study suggests that rTMS may have value in the treatment of episodes of depressive relapse with little reduction in efficacy over time.
BACKGROUND: The efficacy of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression has been assessed in a number of acute treatment trials during the last 10 years. Little is known about the long-term impact of the treatment on the disorder and its effectiveness when applied for repeated relapses of depression over time. METHOD: Nineteen patients who had previously responded to rTMS in clinical trials received treatment with rTMS for a total of 30 episodes of depressive relapse. RESULTS: Approximately 10 months elapsed between treatment episodes. The majority of patients achieved a significant improvement in each treatment course with significant improvements achieved in patients treated with both low-frequency right-sided rTMS and high-frequency left-sided rTMS. CONCLUSIONS: The study suggests that rTMS may have value in the treatment of episodes of depressive relapse with little reduction in efficacy over time.
Authors: Michael S Kelly; Albino J Oliveira-Maia; Margo Bernstein; Adam P Stern; Daniel Z Press; Alvaro Pascual-Leone; Aaron D Boes Journal: J Neuropsychiatry Clin Neurosci Date: 2016-11-30 Impact factor: 2.198
Authors: Antonio Mantovani; Martina Pavlicova; David Avery; Ziad Nahas; William M McDonald; Chandra D Wajdik; Paul E Holtzheimer; Mark S George; Harold A Sackeim; Sarah H Lisanby Journal: Depress Anxiety Date: 2012-06-11 Impact factor: 6.505
Authors: M Mennemeier; T Munn; M Allensworth; J K Lenow; G Brown; S Allen; J Dornhoffer; D K Williams Journal: Hear Res Date: 2012-04-01 Impact factor: 3.208
Authors: Astrid Lehner; Martin Schecklmann; Timm B Poeppl; Peter M Kreuzer; Juliette Peytard; Elmar Frank; Berthold Langguth Journal: Biomed Res Int Date: 2015-10-25 Impact factor: 3.411