| Literature DB >> 16910644 |
Chikashi Kanazawa1, Shin Kamijo, Yoshinori Yamamoto.
Abstract
The copper-catalyzed reaction between two different isocyanides produces the corresponding heteroaromatization products, imidazoles, in good yields. The reaction proceeds most probably through the activation of the sp3 C-H bond in the isocyanides by a copper catalyst, followed by a [3 + 2] cycloaddition between the cuprioisocyanide intermediates and arylisocyanides.Entities:
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Year: 2006 PMID： 16910644 DOI： 10.1021/ja0617439
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419