Literature DB >> 1691059

Erythrocytes of patients with paroxysmal nocturnal haemoglobinuria acquire resistance to complement attack by purified 20-kD homologous restriction factor.

N Okada1, R Harada, H Okada.   

Abstract

A 20-kD homologous restriction factor (HRF20) which is a membrane inhibitor of the terminal stage of human complement action can be detected by the monoclonal antibody 1F5, and is deficient on abnormal erythrocytes as well as leucocytes from patients with paroxysmal nocturnal haemoglobinuria (PNH). The erythrocytes of PNH patients significantly improved their resistance to homologous complement after adsorption of purified HRF20.

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Year:  1990        PMID： 1691059      PMCID： PMC1535229          DOI： 10.1111/j.1365-2249.1990.tb06449.x

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  21 in total

1.  Isolation of a human erythrocyte membrane protein capable of inhibiting expression of homologous complement transmembrane channels.

Authors:  L S Zalman; L M Wood; H J Müller-Eberhard
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

2.  Isolation from human erythrocytes of a new membrane protein which inhibits the formation of complement transmembrane channels.

Authors:  Y Sugita; Y Nakano; M Tomita
Journal:  J Biochem       Date:  1988-10       Impact factor: 3.387

3.  Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria.

Authors:  M H Holguin; L R Fredrick; N J Bernshaw; L A Wilcox; C J Parker
Journal:  J Clin Invest       Date:  1989-07       Impact factor: 14.808

4.  The "sugar-water" test for paroxysmal nocturnal hemoglobinuria.

Authors:  R C Hartmann; D E Jenkins
Journal:  N Engl J Med       Date:  1966-07-21       Impact factor: 91.245

5.  Homologous species restriction in lysis of human erythrocytes: a membrane-derived protein with C8-binding capacity functions as an inhibitor.

Authors:  S Schönermark; E W Rauterberg; M L Shin; S Löke; D Roelcke; G M Hänsch
Journal:  J Immunol       Date:  1986-03-01       Impact factor: 5.422

6.  Prevention of complement activation on the homologous cell membrane of nucleated cells as well as erythrocytes.

Authors:  H Okada; H Tanaka; N Okada
Journal:  Eur J Immunol       Date:  1983-04       Impact factor: 5.532

7.  The mechanism of action of decay-accelerating factor (DAF). DAF inhibits the assembly of C3 convertases by dissociating C2a and Bb.

Authors:  T Fujita; T Inoue; K Ogawa; K Iida; N Tamura
Journal:  J Exp Med       Date:  1987-11-01       Impact factor: 14.307

8.  Paroxysmal nocturnal hemoglobinuria: deficiency in factor H-like functions of the abnormal erythrocytes.

Authors:  M K Pangburn; R D Schreiber; J S Trombold; H J Müller-Eberhard
Journal:  J Exp Med       Date:  1983-06-01       Impact factor: 14.307

9.  Deficiency of the homologous restriction factor in paroxysmal nocturnal hemoglobinuria.

Authors:  L S Zalman; L M Wood; M M Frank; H J Müller-Eberhard
Journal:  J Exp Med       Date:  1987-02-01       Impact factor: 14.307

10.  Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes.

Authors:  M E Medof; T Kinoshita; V Nussenzweig
Journal:  J Exp Med       Date:  1984-11-01       Impact factor: 14.307
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  5 in total

1.  CD59 blocks not only the insertion of C9 into MAC but inhibits ion channel formation by homologous C5b-8 as well as C5b-9.

Authors:  Imre Farkas; Lajos Baranyi; Yasushige Ishikawa; Noriko Okada; Csaba Bohata; Denes Budai; Atsuo Fukuda; Masaki Imai; Hidechika Okada
Journal:  J Physiol       Date:  2002-03-01       Impact factor: 5.182

2.  Intercellular transfer of a glycosylphosphatidylinositol (GPI)-linked protein: release and uptake of CD4-GPI from recombinant adeno-associated virus-transduced HeLa cells.

Authors:  S M Anderson; G Yu; M Giattina; J L Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-11       Impact factor: 11.205

Review 3.  Membrane proteins that protect against complement lysis.

Authors:  B P Morgan; S Meri
Journal:  Springer Semin Immunopathol       Date:  1994

4.  Paroxysmal nocturnal hemoglobinuria: pathophysiology, natural history and treatment options in the era of biological agents.

Authors:  Antonio M Risitano; Bruno Rotoli
Journal:  Biologics       Date:  2008-06

Review 5.  Relating GPI-Anchored Ly6 Proteins uPAR and CD59 to Viral Infection.

Authors:  Jingyou Yu; Vaibhav Murthy; Shan-Lu Liu
Journal:  Viruses       Date:  2019-11-14       Impact factor: 5.048
  5 in total

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