Literature DB >> 1690805

A subset of antibodies from the sera of patients with systemic lupus erythematosus react with vimentin and DNA.

A Sánchez1, C Ossorio, J M Alvaro-Gracia, R Padilla, J Avila.   

Abstract

Sera from patients with systemic lupus erythematosus were tested for the simultaneous presence of antibodies to intermediate filaments (vimentin) and to DNA, using radioimmunoassay and immunofluorescence techniques. Our results indicate that 3 of 17 sera tested contain an IgM population which recognizes an antigenic determinant common to vimentin and DNA by a solid phase immunoassay.

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Year:  1990        PMID: 1690805

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  2 in total

Review 1.  The cytoskeleton and its importance as a mediator of inflammation.

Authors:  K R Rogers; C J Morris; D R Blake
Journal:  Ann Rheum Dis       Date:  1992-04       Impact factor: 19.103

2.  Vimentin compartmentalization in discoid lupus.

Authors:  Ana Maria Abreu-Velez; Graham Smith; Michael S Howard
Journal:  N Am J Med Sci       Date:  2010-02
  2 in total

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