Literature DB >> 16903921

Natural regulatory T cells and parasites: a common quest for host homeostasis.

Yasmine Belkaid1, Rebecca B Blank, Isabelle Suffia.   

Abstract

This review discusses the roles played by natural CD4+ CD25+ regulatory T cells (natural Tregs) during parasitic infections. Natural Tregs may limit the magnitude of effector responses, which may result in failure to adequately control infection. However, natural Tregs also help to limit collateral tissue damage caused by vigorous antimicrobial immune responses. We discuss the hypothesis that parasites have evolved means to manipulate the host's natural Treg population, thereby generating conditions that secure survival in their vertebrate host for an extended period of time.

Entities:  

Mesh：

Year:  2006        PMID： 16903921     DOI： 10.1111/j.0105-2896.2006.00409.x

Source DB:  PubMed          Journal:  Immunol Rev        ISSN： 0105-2896            Impact factor:   12.988


  52 in total

1.  [Cutaneous leishmaniasis].

Authors:  E von Stebut; C Sunderkötter
Journal:  Hautarzt       Date:  2007-05       Impact factor: 0.751

Review 2.  The Foxp3+ regulatory T cell: a jack of all trades, master of regulation.

Authors:  Qizhi Tang; Jeffrey A Bluestone
Journal:  Nat Immunol       Date:  2008-03       Impact factor: 25.606

3.  NIAID workshop on immunity to malaria: addressing immunological challenges.

Authors:  Alison Deckhut Augustine; B Fenton Hall; Wolfgang W Leitner; Annie X Mo; Tonu M Wali; Anthony S Fauci
Journal:  Nat Immunol       Date:  2009-07       Impact factor: 25.606

4.  Novel and functional regulatory SNPs in the promoter region of FOXP3 gene in a Gabonese population.

Authors:  Susanne A Hanel; T P Velavan; Peter G Kremsner; Jürgen F J Kun
Journal:  Immunogenetics       Date:  2011-04-07       Impact factor: 2.846

5.  Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection.

Authors:  Julie Ribot; Geneviève Enault; Sylvie Pilipenko; Anne Huchenq; Maryline Calise; Denis Hudrisier; Paola Romagnoli; Joost P M van Meerwijk
Journal:  J Immunol       Date:  2007-11-15       Impact factor: 5.422

6.  Functional Foxp3+ CD4+ CD25(Bright+) "natural" regulatory T cells are abundant in rabbit conjunctiva and suppress virus-specific CD4+ and CD8+ effector T cells during ocular herpes infection.

Authors:  Anthony B Nesburn; Ilham Bettahi; Gargi Dasgupta; Alami Aziz Chentoufi; Xiuli Zhang; Sylvaine You; Naoyuki Morishige; Andrew J Wahlert; Donald J Brown; James V Jester; Steven L Wechsler; Lbachir BenMohamed
Journal:  J Virol       Date:  2007-05-02       Impact factor: 5.103

7.  Anti-CD25 antibody-mediated depletion of effector T cell populations enhances susceptibility of mice to acute but not chronic Toxoplasma gondii infection.

Authors:  Kevin N Couper; Paula A Lanthier; Georgia Perona-Wright; Lawrence W Kummer; Wangxue Chen; Stephen T Smiley; Markus Mohrs; Lawrence L Johnson
Journal:  J Immunol       Date:  2009-04-01       Impact factor: 5.422

8.  Regulatory T cells are locally induced during intravaginal infection of mice with Neisseria gonorrhoeae.

Authors:  Mónica Imarai; Enzo Candia; Carolina Rodriguez-Tirado; Javier Tognarelli; Mirka Pardo; Tomas Pérez; Daniel Valdés; Sebastián Reyes-Cerpa; Pablo Nelson; Claudio Acuna-Castillo; Kevin Maisey
Journal:  Infect Immun       Date:  2008-09-29       Impact factor: 3.441

9.  Why functional pre-erythrocytic and bloodstage malaria vaccines fail: a meta-analysis of fully protective immunizations and novel immunological model.

Authors:  D Lys Guilbride; Pawel Gawlinski; Patrick D L Guilbride
Journal:  PLoS One       Date:  2010-05-19       Impact factor: 3.240

10.  Integrated cytokine and metabolic analysis of pathological responses to parasite exposure in rodents.

Authors:  Jasmina Saric; Jia V Li; Jonathan R Swann; Jürg Utzinger; Gail Calvert; Jeremy K Nicholson; Stephan Dirnhofer; Maggie J Dallman; Magda Bictash; Elaine Holmes
Journal:  J Proteome Res       Date:  2010-05-07       Impact factor: 4.466
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.