Literature DB >> 16903141

An outline of the neuropathology of transmissible spongiform encephalopathies (prion diseases).

Paweł P Liberski1, James W Ironside.   

Abstract

We review here the basic neuropathology of transmissible spongiform encephalopathies (TSE) or prion diseases. The classic hallmark of TSE neuropathology is a combination (in different proportions in different diseases) of spongiform change, astrocytosis, neuronal loss and amyloid plaques. Immunohistochemically, accumulation of the abnormal isoform of prion protein (PrP(sc) or PrP(d)) is regarded as a diagnostic for TSE. We also review the peculiarities of kuru, variant Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker disease.

Entities:  

Mesh：

Year:  2004        PMID： 16903141

Source DB:  PubMed          Journal:  Folia Neuropathol        ISSN： 1509-572X            Impact factor:   2.038


  11 in total

Review 1.  Prion neurotoxicity.

Authors:  Nhat T T Le; Bei Wu; David A Harris
Journal:  Brain Pathol       Date:  2019-01-17       Impact factor: 6.508

2.  Contribution of vascular pathology to the clinical expression of dementia.

Authors:  Dorothea Strozyk; Dennis W Dickson; Richard B Lipton; Mindy Katz; Carol A Derby; Sunhee Lee; Cuiling Wang; Joe Verghese
Journal:  Neurobiol Aging       Date:  2008-11-08       Impact factor: 4.673

Review 3.  Monocyte/macrophage trafficking in acquired immunodeficiency syndrome encephalitis: lessons from human and nonhuman primate studies.

Authors:  Tracy Fischer-Smith; Christie Bell; Sidney Croul; Mark Lewis; Jay Rappaport
Journal:  J Neurovirol       Date:  2008-08       Impact factor: 2.643

4.  Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrPres level disparity.

Authors:  Victoria Lewis; Cathryn L Haigh; Colin L Masters; Andrew F Hill; Victoria A Lawson; Steven J Collins
Journal:  Mol Neurodegener       Date:  2012-04-26       Impact factor: 14.195

5.  Subtype and regional-specific neuroinflammation in sporadic creutzfeldt-jakob disease.

Authors:  Franc Llorens; Irene López-González; Katrin Thüne; Margarita Carmona; Saima Zafar; Olivier Andréoletti; Inga Zerr; Isidre Ferrer
Journal:  Front Aging Neurosci       Date:  2014-08-04       Impact factor: 5.750

6.  Identification of clinical target areas in the brainstem of prion-infected mice.

Authors:  Ilaria Mirabile; Parmjit S Jat; Sebastian Brandner; John Collinge
Journal:  Neuropathol Appl Neurobiol       Date:  2015-04-23       Impact factor: 8.090

7.  Treatment with a non-toxic, self-replicating anti-prion delays or prevents prion disease in vivo.

Authors:  R Diaz-Espinoza; R Morales; L Concha-Marambio; I Moreno-Gonzalez; F Moda; C Soto
Journal:  Mol Psychiatry       Date:  2017-06-20       Impact factor: 15.992

8.  iPS Cell Cultures from a Gerstmann-Sträussler-Scheinker Patient with the Y218N PRNP Mutation Recapitulate tau Pathology.

Authors:  Andreu Matamoros-Angles; Lucía Mayela Gayosso; Yvonne Richaud-Patin; Angelique di Domenico; Cristina Vergara; Arnau Hervera; Amaya Sousa; Natalia Fernández-Borges; Antonella Consiglio; Rosalina Gavín; Rakel López de Maturana; Isidro Ferrer; Adolfo López de Munain; Ángel Raya; Joaquín Castilla; Rosario Sánchez-Pernaute; José Antonio Del Río
Journal:  Mol Neurobiol       Date:  2017-05-02       Impact factor: 5.590

9.  The olfactory bulb as the entry site for prion-like propagation in neurodegenerative diseases.

Authors:  Nolwen L Rey; Daniel W Wesson; Patrik Brundin
Journal:  Neurobiol Dis       Date:  2016-12-20       Impact factor: 5.996

10.  A Neuronal Culture System to Detect Prion Synaptotoxicity.

Authors:  Cheng Fang; Thibaut Imberdis; Maria Carmen Garza; Holger Wille; David A Harris
Journal:  PLoS Pathog       Date:  2016-05-26       Impact factor: 6.823
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