Literature DB >> 16902874

Topical negative pressure therapy in wounds after cardiothoracic surgery: successful experience supported by literature.

P Segers1, A P de Jong, J J Kloek, C M van der Horst, L Spanjaard, B A de Mol.   

Abstract

BACKGROUND: Patients undergoing cardiothoracic surgery are at substantial risk of developing surgical site infections (SSI). SSI is not only associated with an increased morbidity but also with high mortality. Topical negative pressure therapy (TNP) is a promising method for treating surgical site defects (SSD). In recent years, we have gained a wide experience with TNP in a great variety of SSD.
METHODS: We completed a prospective follow-up report of all patients treated with TNP after cardiothoracic surgery at the Academic Medical Centre Amsterdam, a university hospital. A review of the current evidence for TNP in cardiothoracic surgery is presented.
RESULTS: Between August 2000 and March 2005, TNP was used in 105 patients in 113 SSD. As we gained more experience, we saw a decline in hospital stay ( P < 0.0001) and duration of TNP therapy. Surgical closure was performed in 62 % of patients using simple surgical (reconstructive) techniques. Therapy-related complications were rare (n = 1).
CONCLUSION: Based on clinical findings and supported by the research presented, the treatment modality of choice for SSD after cardiothoracic surgery is TNP.

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Year:  2006        PMID: 16902874     DOI: 10.1055/s-2006-924003

Source DB:  PubMed          Journal:  Thorac Cardiovasc Surg        ISSN: 0171-6425            Impact factor:   1.827


  4 in total

Review 1.  Major bleeding during negative pressure wound/V.A.C.®--therapy for postsurgical deep sternal wound infection--a critical appraisal.

Authors:  Jan J van Wingerden; Patrique Segers; Lilian Jekel
Journal:  J Cardiothorac Surg       Date:  2011-09-29       Impact factor: 1.637

2.  Propofol inhibits pressure-stimulated macrophage phagocytosis via the GABAA receptor and dysregulation of p130cas phosphorylation.

Authors:  Hiroe Shiratsuchi; Yasser Kouatli; Guang Xiang Yu; Harold M Marsh; Marc D Basson
Journal:  Am J Physiol Cell Physiol       Date:  2009-04-08       Impact factor: 4.249

Review 3.  Poststernotomy mediastinitis: a classification to initiate and evaluate reconstructive management based on evidence from a structured review.

Authors:  Jan J van Wingerden; Dirk T Ubbink; Chantal M A M van der Horst; Bas A J M de Mol
Journal:  J Cardiothorac Surg       Date:  2014-11-23       Impact factor: 1.637

Review 4.  Prevention, Diagnosis and Management of Post-Surgical Mediastinitis in Adults Consensus Guidelines of the Spanish Society of Cardiovascular Infections (SEICAV), the Spanish Society of Thoracic and Cardiovascular Surgery (SECTCV) and the Biomedical Research Centre Network for Respiratory Diseases (CIBERES).

Authors:  Emilio Bouza; Arístides de Alarcón; María Carmen Fariñas; Juan Gálvez; Miguel Ángel Goenaga; Francisco Gutiérrez-Díez; Javier Hortal; José Lasso; Carlos A Mestres; José M Miró; Enrique Navas; Mercedes Nieto; Antonio Parra; Enrique Pérez de la Sota; Hugo Rodríguez-Abella; Marta Rodríguez-Créixems; Jorge Rodríguez-Roda; Gemma Sánchez Espín; Dolores Sousa; Carlos Velasco García de Sierra; Patricia Muñoz; Martha Kestler
Journal:  J Clin Med       Date:  2021-11-26       Impact factor: 4.241

  4 in total

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