Literature DB >> 16902678

Caudal epidural injections with sarapin or steroids in chronic low back pain.

L Manchikanti1, V Pampati, J J Rivera, C Beyer, K S Damron, R C Barnhill.   

Abstract

Epidural steroid injections are the most commonly used procedures to manage chronic low back pain in interventional pain management settings. Approaches available to access the epidural space in the lumbosacral spine include the interlaminar, transforaminal, and caudal. The overall effectiveness of epidural steroid injections has been highly variable. This study included 65 patients who underwent diagnostic facet joint nerve blocks utilizing comparative local anesthetic blocks and were shown to be negative for facet joint pain and other problems such as sacroiliac joint pain before enrollment into the study. They were randomly selected from 105 patients negative for facet joint pain allocated into three groups, with Group I consisting of 15 patients comprising a convenience control sample treated conservatively; Group II, consisting of 22 patients treated with caudal epidural with local anesthetic and Sarapin(R); and Group III, consisting of 33 patients treated with caudal epidural with a mixture of local anesthetic, and betamethasone. The study period lasted for 3 years. Results showed that there was significant improvement in patients receiving caudal epidural injections, with a decrease in pain associated with improved physical, functional and mental status; and decreased narcotic intake combined with return to work. The study showed that at 1 month 96% of the patients evaluated showed significant improvement, which declined to 56% at 3 months and 16% at 6 months, with administration of 1 to 3 injections. Cumulative relief with 1 to 12 injections was noted in 96% of the patients at 1 month, 95% at 3 months, 85% at 6 months, and 67% at 1 year. The study also showed cost effectiveness of this treatment, with a cost of $ 2550 for 1-year improvement of quality of life . In conclusion, caudal epidural injections with steroids or Sarapin are an effective modality of treatment in managing chronic, persistent low back pain that fails to respond to conservative modalities of treatments and is also negative for facet joint pain. The treatment is not only effective clinically but also is cost effective.

Entities:  

Year:  2001        PMID: 16902678

Source DB:  PubMed          Journal:  Pain Physician        ISSN: 1533-3159            Impact factor:   4.965


  7 in total

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Authors:  J W Lee; H I Shin; S Y Park; G Y Lee; H S Kang
Journal:  AJNR Am J Neuroradiol       Date:  2010-07-08       Impact factor: 3.825

Review 2.  Transforaminal injection of corticosteroids for lumbar radiculopathy: systematic review and meta-analysis.

Authors:  Nasir A Quraishi
Journal:  Eur Spine J       Date:  2011-09-04       Impact factor: 3.134

Review 3.  Pharmacological management of chronic lower back pain: a review of cost effectiveness.

Authors:  Marion Haas; Richard De Abreu Lourenco
Journal:  Pharmacoeconomics       Date:  2015-06       Impact factor: 4.981

4.  Fluoroscopic lumbar interlaminar epidural injections in managing chronic lumbar axial or discogenic pain.

Authors:  Laxmaiah Manchikanti; Kimberly A Cash; Carla D McManus; Vidyasagar Pampati; Ramsin Benyamin
Journal:  J Pain Res       Date:  2012-08-24       Impact factor: 3.133

5.  [ISRCTN 16558617] A randomized, controlled trial of spinal endoscopic adhesiolysis in chronic refractory low back and lower extremity pain.

Authors:  Laxmaiah Manchikanti; Mark V Boswell; Jose J Rivera; Vidya Sagar Pampati; Kim S Damron; Carla D McManus; Doris E Brandon; Sue R Wilson
Journal:  BMC Anesthesiol       Date:  2005-07-06       Impact factor: 2.217

6.  Resolution of Recurrent Oro-facial Herpes Simplex Using a Topical Botanical Gel: A Case Report.

Authors:  Erik O Nelson; Guillermo G Ruiz; Adam F Kozin; Tiffany C Turner; Edith V Langland; Jeffrey O Langland
Journal:  Yale J Biol Med       Date:  2020-06-29

Review 7.  Secondary Metabolites with Biomedical Applications from Plants of the Sarraceniaceae Family.

Authors:  Ileana Miclea
Journal:  Int J Mol Sci       Date:  2022-08-30       Impact factor: 6.208

  7 in total

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