Literature DB >> 16902581

Will you let me use your nucleus? How Agrobacterium gets its T-DNA expressed in the host plant cell.

Benoît Lacroix1, Jianxiong Li, Tzvi Tzfira, Vitaly Citovsky.   

Abstract

Agrobacterium is the only known bacterium capable of natural DNA transfer into a eukaryotic host. The genes transferred to host plants are contained on a T-DNA (transferred DNA) molecule, the transfer of which begins with its translocation, along with several effector proteins, from the bacterial cell to the host-cell cytoplasm. In the host cytoplasm, the T-complex is formed from a single-stranded copy of the T-DNA (T-strand) associated with several bacterial and host proteins and it is imported into the host nucleus via interactions with the host nuclear import machinery. Once inside the nucleus, the T-complex is most likely directed to the host genome by associating with histones. Finally, the chromatin-associated T-complex is uncoated from its escorting proteins prior to the conversion of the T-strand to a double-stranded form and its integration into the host genome.

Mesh:

Substances:

Year:  2006        PMID: 16902581     DOI: 10.1139/y05-108

Source DB:  PubMed          Journal:  Can J Physiol Pharmacol        ISSN: 0008-4212            Impact factor:   2.273


  10 in total

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Journal:  Eukaryot Cell       Date:  2008-06-06

2.  Composition, roles, and regulation of cullin-based ubiquitin e3 ligases.

Authors:  Christina M Choi; William M Gray; Sutton Mooney; Hanjo Hellmann
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3.  Conjugative DNA transfer into human cells by the VirB/VirD4 type IV secretion system of the bacterial pathogen Bartonella henselae.

Authors:  Gunnar Schröder; Ralf Schuelein; Maxime Quebatte; Christoph Dehio
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4.  Agrobacterium aiming for the host chromatin: Host and bacterial proteins involved in interactions between T-DNA and plant nucleosomes.

Authors:  Benoît Lacroix; Vitaly Citovsky
Journal:  Commun Integr Biol       Date:  2009

5.  RNAi-mediated gene silencing reveals involvement of Arabidopsis chromatin-related genes in Agrobacterium-mediated root transformation.

Authors:  Yan Ma Crane; Stanton B Gelvin
Journal:  Proc Natl Acad Sci U S A       Date:  2007-09-07       Impact factor: 11.205

6.  Genetic reprogramming of host cells by bacterial pathogens.

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Journal:  F1000 Biol Rep       Date:  2009-10-29

7.  Overexpression of several Arabidopsis histone genes increases agrobacterium-mediated transformation and transgene expression in plants.

Authors:  Gabriela N Tenea; Joerg Spantzel; Lan-Ying Lee; Yanmin Zhu; Kui Lin; Susan J Johnson; Stanton B Gelvin
Journal:  Plant Cell       Date:  2009-10-09       Impact factor: 11.277

Review 8.  Expression of complete metabolic pathways in transgenic plants.

Authors:  Alexander Krichevsky; Adi Zaltsman; Lisa King; Vitaly Citovsky
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9.  Traversing the Cell: Agrobacterium T-DNA's Journey to the Host Genome.

Authors:  Stanton B Gelvin
Journal:  Front Plant Sci       Date:  2012-03-26       Impact factor: 5.753

Review 10.  Agrobacterium infection and plant defense-transformation success hangs by a thread.

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Journal:  Front Plant Sci       Date:  2013-12-18       Impact factor: 5.753

  10 in total

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