Literature DB >> 16901813

Phosphodiesterase-I inhibitor quinovic acid glycosides from Bridelia ndellensis.

M Mostafa1, Nilufar Nahar, M Mosihuzzaman, Selestin D Sokeng, Naheed Fatima, M Iqbal Choudhary.   

Abstract

Quinovic acid-3-O-alpha-L-rhamnopyranoside (1), quinovic acid-3-O-beta-D-fucopyranoside (2), quinovic acid-3-O-beta-D-glucopyranosyl (1 --> 4)-beta-D-fucopyranoside (3), methyl gallate (4) and ethyl gallate (5) were isolated from the ethyl acetate extract of Bridelia ndellensis barks by fractionation. Compounds 1-3 showed significant inhibitory activity against snake venom phosphodiesterase-I.

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Year:  2006        PMID： 16901813     DOI： 10.1080/14786410600661658

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  3 in total

1.  Chemical and biological studies on Bridelia ferruginea grown in Nigeria.

Authors:  Michael Afolayan; Radhakrishnan Srivedavyasasri; Olayinka T Asekun; Oluwole B Familoni; Samir A Ross
Journal:  Nat Prod Res       Date:  2018-02-19       Impact factor: 2.861

2.  Quinovic Acid Impedes Cholesterol Dyshomeostasis, Oxidative Stress, and Neurodegeneration in an Amyloid-β-Induced Mouse Model.

Authors:  Kamran Saeed; Shahid Ali Shah; Rahat Ullah; Sayed Ibrar Alam; Jun Sung Park; Samreen Saleem; Myeung Hoon Jo; Min Woo Kim; Jong Ryeal Hahm; Myeong Ok Kim
Journal:  Oxid Med Cell Longev       Date:  2020-11-20       Impact factor: 6.543

Review 3.  Inhibition of phosphodiesterase: A novel therapeutic target for the treatment of mild cognitive impairment and Alzheimer's disease.

Authors:  Jianwen Sheng; Shanjin Zhang; Lule Wu; Gajendra Kumar; Yuanhang Liao; Pratap Gk; Huizhen Fan
Journal:  Front Aging Neurosci       Date:  2022-10-04       Impact factor: 5.702
  3 in total

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