| Literature DB >> 16901776 |
Abstract
Integrins modulate signaling by growth factor receptors, but their role during tumorigenesis is not clear. Guo et al. (2006) now demonstrate that alpha 6 beta 4 integrin cooperates with ErbB2 in the formation of mammary tumors and discover distinct pathways that regulate cellular proliferation and adhesion downstream of the ErbB2-integrin complex.Entities:
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Year: 2006 PMID： 16901776 DOI： 10.1016/j.cell.2006.07.020
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582