Literature DB >> 1690149

Monoclonal antibodies against the human lymphocyte differentiation antigen CD 76 bind to gangliosides.

B Kniep1, P F Mühlradt, B Dörken, G Moldenhauer, R Vilella, R Schwartz-Albiez.   

Abstract

Two monoclonal antibodies, HD 66 and CRIS-4, by which the new CD 76 B-cell-associated cluster was defined, bound to several gangliosides (sialic acid containing glycolipids) of different polarity. One of the gangliosides recognized by HD 66 could be identified as NeuAc alpha 2-6Gal beta 1-4GlcNAc beta 1-3Gal beta 1-4Glc-beta 1-1'Cer. This antigen was enzymatically synthesized. Sialidase treatment of the ganglioside antigens abolished binding of HD 66 and CRIS-4.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 1690149     DOI： 10.1016/0014-5793(90)80588-a

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  3 in total

Review 1.  Identification and characterization of CD8+ suppressor T cells.

Authors:  James C Zimring; Judith A Kapp
Journal:  Immunol Res       Date:  2004       Impact factor: 2.829

2.  The HB-6, CDw75, and CD76 differentiation antigens are unique cell-surface carbohydrate determinants generated by the beta-galactoside alpha 2,6-sialyltransferase.

Authors:  B J Bast; L J Zhou; G J Freeman; K J Colley; T J Ernst; J M Munro; T F Tedder
Journal:  J Cell Biol       Date:  1992-01       Impact factor: 10.539

3.  Monoclonal antibodies VIB-E3, IB5 and HB9 to the leucocyte/epithelial antigen CD24 resemble BA-1 in recognizing sialic acid-dependent epitope(s). Evidence that VIB-E3 recognizes NeuAc alpha 2-6GalNAc and NeuAc alpha 2-6Gal sequences.

Authors:  M Larkin; W Knapp; M S Stoll; H Mehmet; T Feizi
Journal:  Clin Exp Immunol       Date:  1991-09       Impact factor: 4.330
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.