Literature DB >> 16900887

Haptoglobin gene promoter polymorphism and haplotypes are unique in different populations.

Kwesi Teye1, Mikiko Soejima, Isaac K E Quaye, Hao Pang, Makoto Tsuneoka, Yoshiro Koda, Hiroshi Kimura.   

Abstract

We investigated the distribution of haptoglobin (HP) alleles and haplotypes among Africans (Ghanaians), Europeans (from South Africa), and Chinese. HP*1F was present only in Africans and Europeans, whereas HP*del was unique to Chinese. Six base substitutions at the promoter region were population specific. Only 3 out of 18 haplotypes were shared among the populations. A probable application of HP in human population genetics appears legitimate.

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Year:  2006        PMID： 16900887     DOI： 10.1353/hub.2006.0029

Source DB:  PubMed          Journal:  Hum Biol        ISSN： 0018-7143            Impact factor:   0.553


  3 in total

1.  Single nucleotide polymorphisms of the haptoglobin gene in non-small cell lung cancer treated with personalized peptide vaccination.

Authors:  Kayoko Waki; Teppei Yamada; Koichi Yoshiyama; Yasuhiro Terazaki; Shinjiro Sakamoto; Shunichi Sugawara; Shinzo Takamori; Kyogo Itoh; Akira Yamada
Journal:  Oncol Lett       Date:  2016-12-07       Impact factor: 2.967

2.  Haplotype association between haptoglobin (Hp2) and Hp promoter SNP (A-61C) may explain previous controversy of haptoglobin and malaria protection.

Authors:  Sharon E Cox; Conor Doherty; Sarah H Atkinson; Chidi V Nweneka; Anthony J C Fulford; Hala Ghattas; Kirk A Rockett; Dominic P Kwiatkowski; Andrew M Prentice
Journal:  PLoS One       Date:  2007-04-11       Impact factor: 3.240

3.  Haptoglobin polymorphisms in Latin American populations.

Authors:  Mikiko Soejima; Yoshiro Koda
Journal:  Sci Rep       Date:  2020-08-13       Impact factor: 4.379
  3 in total

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