OBJECTIVE: To compare the serum thiocyanate levels in smokers, passive smokers and never smokers. METHODS: Serum thiocyanate was analyzed on 135 self reported smokers, never smokers and passive smokers by UV-Spectrophotometry (Manual method of Bowler). RESULTS: The mean serum thiocyanate concentration (112 +/- 36.6 micromol/L) of smokers was significantly higher (p value < 0.001) as compared to passive (55 +/- 16.1 micromol/L) and never smokers (41 +/- 6.6 micromol/L). The serum thiocyanate of female smokers (133 + 28.7 micromol/L) was higher (p value < 0.05) than male smokers (103 +/- 36.3 miccromol/L). Serum thiocyanate showed 91% sensitivity, 80% specificity and 84% accuracy at > or = 60 micromol/L for smokers. CONCLUSION: Serum thiocyanate is significantly higher in smokers than passive and never smokers. Serum thiocyanate at > or = 60 micromol/L may be considered as cutoff value for distinguishing smokers from non-smokers for future studies.
OBJECTIVE: To compare the serum thiocyanate levels in smokers, passive smokers and never smokers. METHODS: Serum thiocyanate was analyzed on 135 self reported smokers, never smokers and passive smokers by UV-Spectrophotometry (Manual method of Bowler). RESULTS: The mean serum thiocyanate concentration (112 +/- 36.6 micromol/L) of smokers was significantly higher (p value < 0.001) as compared to passive (55 +/- 16.1 micromol/L) and never smokers (41 +/- 6.6 micromol/L). The serum thiocyanate of female smokers (133 + 28.7 micromol/L) was higher (p value < 0.05) than male smokers (103 +/- 36.3 miccromol/L). Serum thiocyanate showed 91% sensitivity, 80% specificity and 84% accuracy at > or = 60 micromol/L for smokers. CONCLUSION: Serum thiocyanate is significantly higher in smokers than passive and never smokers. Serum thiocyanate at > or = 60 micromol/L may be considered as cutoff value for distinguishing smokers from non-smokers for future studies.
Authors: Sanna Turunen; Johanna Huhtakangas; Tomi Nousiainen; Maarit Valkealahti; Jukka Melkko; Juha Risteli; Petri Lehenkari Journal: Arthritis Res Ther Date: 2016-10-20 Impact factor: 5.156
Authors: Jessie P Buckley; Emily S Barrett; Paloma I Beamer; Deborah H Bennett; Michael S Bloom; Timothy R Fennell; Rebecca C Fry; William E Funk; Ghassan B Hamra; Stephen S Hecht; Kurunthachalam Kannan; Ramsunder Iyer; Margaret R Karagas; Kristen Lyall; Patrick J Parsons; Edo D Pellizzari; Antonio J Signes-Pastor; Anne P Starling; Aolin Wang; Deborah J Watkins; Mingyu Zhang; Tracey J Woodruff Journal: J Expo Sci Environ Epidemiol Date: 2020-02-17 Impact factor: 6.371