Literature DB >> 16900332

Sclerotiorin, from Penicillium frequentans, a potent inhibitor of aldose reductase.

C Chidananda1, L Jagan Mohan Rao, A P Sattur.   

Abstract

Aldose reductase, the first key enzyme in the polyol pathway, is involved in complications of diabetes. Sclerotiorin, isolated and purified from the fermented broth of Penicillium frequentans, inhibited aldose reductase with an IC(50 )0.4 microM. The inhibitor also showed antibacterial activity against Bacillus spp.

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Year:  2006        PMID： 16900332     DOI： 10.1007/s10529-006-9133-4

Source DB:  PubMed          Journal:  Biotechnol Lett        ISSN： 0141-5492            Impact factor:   2.461


  6 in total

1.  Preparation, Structure, and Potent Antifouling Activity of Sclerotioramine Derivatives.

Authors:  Mei-Yan Wei; Cui-Fang Wang; Kai-Ling Wang; Pei-Yuan Qian; Chang-Yun Wang; Chang-Lun Shao
Journal:  Mar Biotechnol (NY)       Date:  2017-07-07       Impact factor: 3.619

2.  Synthesis of the azaphilones (+)-sclerotiorin and (+)-8-O-methylsclerotiorinamine utilizing (+)-sparteine surrogates in copper-mediated oxidative dearomatization.

Authors:  Andrew R Germain; Daniel M Bruggemeyer; Jianglong Zhu; Cedric Genet; Peter O'Brien; John A Porco
Journal:  J Org Chem       Date:  2011-03-14       Impact factor: 4.354

3.  Bioactive metabolites from Chaetomium aureum: structure elucidation and inhibition of the Hsp90 machine chaperoning activity.

Authors:  Fatima Zahra Kabbaj; Su Lu; My El Abbés Faouzi; Bouchra Meddah; Peter Proksch; Yahya Cherrah; Hans-Josef Altenbach; Amal H Aly; Ahmed Chadli; Abdessamad Debbab
Journal:  Bioorg Med Chem       Date:  2014-11-20       Impact factor: 3.641

4.  Genome Sequencing and Analysis of the Filamentous Fungus Penicillium sclerotiorum 113, Isolated after Hurricane Sandy.

Authors:  Guohua Yin; Yuliang Zhang; Kayla K Pennerman; Sui Sheng T Hua; Qixing Huang; Anping Guo; Zhixin Liu; Joan W Bennett
Journal:  Genome Announc       Date:  2016-11-23

5.  Identification and Validation of an Aspergillus nidulans Secondary Metabolite Derivative as an Inhibitor of the Musashi-RNA Interaction.

Authors:  Lan Lan; Jiajun Liu; Minli Xing; Amber R Smith; Jinan Wang; Xiaoqing Wu; Carl Appelman; Ke Li; Anuradha Roy; Ragul Gowthaman; John Karanicolas; Amber D Somoza; Clay C C Wang; Yinglong Miao; Roberto De Guzman; Berl R Oakley; Kristi L Neufeld; Liang Xu
Journal:  Cancers (Basel)       Date:  2020-08-08       Impact factor: 6.639

Review 6.  Fungal Pigments and Their Roles Associated with Human Health.

Authors:  Lan Lin; Jianping Xu
Journal:  J Fungi (Basel)       Date:  2020-11-12
  6 in total

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