Literature DB >> 16899207

The role of immune tolerance in asthma pathogenesis.

Kurt G Tournoy1, Sharen Provoost, Chris Van Hove, Guy Joos.   

Abstract

Immune-mediated tolerance encompasses a wide spectrum of mechanisms that can prevent unnecessary and potentially harmful inflammatory responses. An increasing number of scientific publications provide proof for the concept that an impairment of immune-tolerance mechanisms might be causally related to the development of unwanted Th2-driven, allergen-induced airway diseases. In this review, we discuss immune tolerance and the evidence supporting its role in asthma pathogenesis.

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Year:  2006        PMID： 16899207     DOI： 10.1007/s11882-996-0018-3

Source DB:  PubMed          Journal:  Curr Allergy Asthma Rep        ISSN： 1529-7322            Impact factor:   4.806


  56 in total

1.  Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity.

Authors:  Omid Akbari; Gordon J Freeman; Everett H Meyer; Edward A Greenfield; Tammy T Chang; Arlene H Sharpe; Gerald Berry; Rosemarie H DeKruyff; Dale T Umetsu
Journal:  Nat Med       Date:  2002-07-29       Impact factor: 53.440

2.  The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.

Authors:  Aysefa Doganci; Tatjana Eigenbrod; Norbert Krug; George T De Sanctis; Michael Hausding; Veit J Erpenbeck; El-Bdaoui Haddad; Hans A Lehr; Edgar Schmitt; Tobias Bopp; Karl-J Kallen; Udo Herz; Steffen Schmitt; Cornelia Luft; Olaf Hecht; Jens M Hohlfeld; Hiroaki Ito; Norihiro Nishimoto; Kazuyuki Yoshizaki; Tadamitsu Kishimoto; Stefan Rose-John; Harald Renz; Markus F Neurath; Peter R Galle; Susetta Finotto
Journal:  J Clin Invest       Date:  2005-02       Impact factor: 14.808

Review 3.  T regulatory cells in allergen-specific immunotherapy.

Authors:  Johan Verhagen; Alison Taylor; Kurt Blaser; Mübeccel Akdis; Cezmi A Akdis
Journal:  Int Rev Immunol       Date:  2005 Sep-Dec       Impact factor: 5.311

4.  Activated CD4+ CD25+ T cells suppress antigen-specific CD4+ and CD8+ T cells but induce a suppressive phenotype only in CD4+ T cells.

Authors:  Detlef Dieckmann; Heidi Plöttner; Stefanie Dotterweich; Gerold Schuler
Journal:  Immunology       Date:  2005-07       Impact factor: 7.397

5.  Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25- T cells.

Authors:  Mindi R Walker; Deborah J Kasprowicz; Vivian H Gersuk; Angele Benard; Megan Van Landeghen; Jane H Buckner; Steven F Ziegler
Journal:  J Clin Invest       Date:  2003-11       Impact factor: 14.808

Review 6.  The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation.

Authors:  James L Riley; Carl H June
Journal:  Blood       Date:  2004-09-07       Impact factor: 22.113

7.  CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma.

Authors:  Omid Akbari; John L Faul; Elisabeth G Hoyte; Gerald J Berry; Jan Wahlström; Mitchell Kronenberg; Rosemarie H DeKruyff; Dale T Umetsu
Journal:  N Engl J Med       Date:  2006-03-16       Impact factor: 91.245

Review 8.  Activation-induced cell death in T cells.

Authors:  Douglas R Green; Nathalie Droin; Michael Pinkoski
Journal:  Immunol Rev       Date:  2003-06       Impact factor: 12.988

9.  Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+CD25+ regulatory T cells is interleukin 10 dependent.

Authors:  Jennifer Kearley; Jane E Barker; Douglas S Robinson; Clare M Lloyd
Journal:  J Exp Med       Date:  2005-11-28       Impact factor: 14.307

10.  Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3.

Authors:  WanJun Chen; Wenwen Jin; Neil Hardegen; Ke-Jian Lei; Li Li; Nancy Marinos; George McGrady; Sharon M Wahl
Journal:  J Exp Med       Date:  2003-12-15       Impact factor: 14.307
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  3 in total

1.  Lung-Infiltrating Foxp3+ Regulatory T Cells Are Quantitatively and Qualitatively Different during Eosinophilic and Neutrophilic Allergic Airway Inflammation but Essential To Control the Inflammation.

Authors:  Eunjung Jang; Quang Tam Nguyen; Sohee Kim; Dongkyun Kim; Thi Hong Nga Le; Karen Keslar; Nina Dvorina; Mark A Aronica; Booki Min
Journal:  J Immunol       Date:  2017-11-01       Impact factor: 5.422

2.  Multiple Inhibitory Pathways Contribute to Lung CD8+ T Cell Impairment and Protect against Immunopathology during Acute Viral Respiratory Infection.

Authors:  John J Erickson; Meredith C Rogers; Sharon J Tollefson; Kelli L Boyd; John V Williams
Journal:  J Immunol       Date:  2016-06-03       Impact factor: 5.422

3.  Re-challenge with ovalbumin failed to induce bronchial asthma in mice with eosinophilic bronchitis.

Authors:  Liyan Chen; Nanshan Zhong; Kefang Lai
Journal:  PLoS One       Date:  2013-09-20       Impact factor: 3.240
  3 in total

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