Literature DB >> 16898827

Novel seco-dibenzopyrrocoline alkaloid from Cryptocarya oubatchensis.

Alix Toribio1, Aurélie Bonfils, Eldra Delannay, Elise Prost, D Harakat, Eric Henon, Bernard Richard, Marc Litaudon, Jean-Marc Nuzillard, Jean-Hugues Renault.   

Abstract

[structure: see text] A novel seco-dibenzopyrrocoline alkaloid, named oubatchensine 6, and five phenanthroindolizidines (1-5) were isolated from Cryptocarya oubatchensis, and their structures were elucidated. Displacement centrifugal partition chromatography was used to purify compounds 1 and 6. Structure determination of the latter was carried out by mass spectrometry, NMR spectroscopy, quantum chemistry, and computer-assisted structure determination. Cytotoxic activity against KB cells was then investigated.

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Year:  2006        PMID： 16898827     DOI： 10.1021/ol061435f

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  (-)-Neocaryachine, an Antiproliferative Pavine Alkaloid from Cryptocarya laevigata, Induces DNA Double-Strand Breaks.

Authors:  Yuki Suzuki; Yohei Saito; Masuo Goto; David J Newman; Barry R O'Keefe; Kuo-Hsiung Lee; Kyoko Nakagawa-Goto
Journal:  J Nat Prod       Date:  2017-01-18       Impact factor: 4.050

2.  Phenolic compounds from Cryptocarya konishii: their cytotoxic and tyrosine kinase inhibitory properties.

Authors:  Fera Kurniadewi; Lia D Juliawaty; Yana M Syah; Sjamsul A Achmad; Euis H Hakim; Kiyotaka Koyama; Kaoru Kinoshita; Kunio Takahashi
Journal:  J Nat Med       Date:  2009-12-11       Impact factor: 2.343

3.  Antiproliferative effects of methanolic extracts of Cryptocarya concinna Hance roots on oral cancer Ca9-22 and CAL 27 cell lines involving apoptosis, ROS induction, and mitochondrial depolarization.

Authors:  Hurng-Wern Huang; Yi-An Chung; Hsun-Shuo Chang; Jen-Yang Tang; Ih-Sheng Chen; Hsueh-Wei Chang
Journal:  ScientificWorldJournal       Date:  2014-10-15

4.  Antimicrobial efficacy and biocompatibility of extracts from Cryptocarya species.

Authors:  Jacqueline de Oliveira Zoccolotti; Alberto José Cavalheiro; Camilla Olga Tasso; Beatriz Ribeiro Ribas; Túlio Morandin Ferrisse; Janaina Habib Jorge
Journal:  PLoS One       Date:  2021-12-31       Impact factor: 3.240
  4 in total

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