SETTING: Tuberculosis (TB) incidence and mortality in Russia have risen dramatically over the past 15 years. OBJECTIVE: To identify risk factors and causes of death among TB patients in Russia. DESIGN: A retrospective study conducted to determine the risk factors and causes of death in patients receiving TB therapy in Tomsk, Siberia. RESULTS: Of 1916 patients who initiated treatment between 1 January 2002 and 31 December 2003, 183 (9.6%) died during treatment, 38 (21%) in the first week of therapy. Twenty-five per cent of deaths were not directly attributable to TB. Risk factors for death included older age, previous treatment for TB, multidrug resistance and alcoholism. CONCLUSIONS: The high death rate during TB treatment observed in this cohort likely reflects an increased risk of dying not only from TB, but also from comorbid conditions, such as alcoholism and cardiovascular disease. Overall, alcoholism and late presentation both contributed substantially to the mortality in this cohort.
SETTING:Tuberculosis (TB) incidence and mortality in Russia have risen dramatically over the past 15 years. OBJECTIVE: To identify risk factors and causes of death among TB patients in Russia. DESIGN: A retrospective study conducted to determine the risk factors and causes of death in patients receiving TB therapy in Tomsk, Siberia. RESULTS: Of 1916 patients who initiated treatment between 1 January 2002 and 31 December 2003, 183 (9.6%) died during treatment, 38 (21%) in the first week of therapy. Twenty-five per cent of deaths were not directly attributable to TB. Risk factors for death included older age, previous treatment for TB, multidrug resistance and alcoholism. CONCLUSIONS: The high death rate during TB treatment observed in this cohort likely reflects an increased risk of dying not only from TB, but also from comorbid conditions, such as alcoholism and cardiovascular disease. Overall, alcoholism and late presentation both contributed substantially to the mortality in this cohort.
Authors: A C Miller; I Y Gelmanova; S Keshavjee; S Atwood; G Yanova; S Mishustin; J J Furin; S S Shin Journal: Int J Tuberc Lung Dis Date: 2012-04-09 Impact factor: 2.373
Authors: Trini A Mathew; Alan L Shields; Aizhan Imasheva; Sonya S Shin; Sergey P Mishustin; Gennady G Peremitin; Aivar K Strelis; Galina V Yanova; Shelly F Greenfield; Jennifer J Furin Journal: Cult Med Psychiatry Date: 2009-12
Authors: I Y Gelmanova; S Keshavjee; V T Golubchikova; V I Berezina; A K Strelis; G V Yanova; S Atwood; M Murray Journal: Bull World Health Organ Date: 2007-09 Impact factor: 9.408
Authors: Trini A Mathew; Sergey A Yanov; Rais Mazitov; Sergey P Mishustin; Aivar K Strelis; Galina V Yanova; Vera T Golubchikova; Dmitry V Taran; Alex Golubkov; Alan L Shields; Shelly F Greenfield; Sonya S Shin Journal: Eur J Public Health Date: 2008-12-26 Impact factor: 3.367
Authors: Mohanarani Suhadev; Beena E Thomas; M Raja Sakthivel; P Murugesan; V Chandrasekaran; Niruparani Charles; R Durga; M Auxilia; Trini A Mathew; Fraser Wares Journal: PLoS One Date: 2011-05-17 Impact factor: 3.240
Authors: Masja Straetemans; Philippe Glaziou; Ana L Bierrenbach; Charalambos Sismanidis; Marieke J van der Werf Journal: PLoS One Date: 2011-06-27 Impact factor: 3.240
Authors: Olufemi O Desalu; Adekunle O Adeoti; Abayomi Fadeyi; Alakija K Salami; Ademola E Fawibe; Olanrewaju O Oyedepo Journal: Tuberc Res Treat Date: 2013-01-14