Hiroshi Goto1, Tatsuro Yamamoto2, Zenzo Ishiyama2, Masahiko Usui2, Shinya Okada3. 1. Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan. goto1115@tokyo-med.ac.jp. 2. Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan. 3. Department of Pathology, Tokyo Medical University, Tokyo, Japan.
Abstract
BACKGROUND: Primary cutaneous adenoid cystic carcinoma is one of the rarest eyelid tumors. CASE: A 39-year-old man presented with a small subcutaneous induration in his left lower eyelid close to the lower lacrimal punctum. OBSERVATIONS: Under a clinical diagnosis of chalazion, the eyelid induration was extracted surgically via the palpebral conjunctiva. Histopathological examination of the extracted tumor revealed proliferation of basaloid cells with a prominent cribriform pattern containing Alcian blue-positive and periodic acid Schiff-positive material, leading to a diagnosis of adenoid cystic carcinoma. The patient subsequently underwent extended radical excision including the lacrimal sac. No recurrence was observed during 20 months after surgery. CONCLUSIONS: Adenoid cystic carcinoma should be considered as a differential diagnosis of eyelid tumors simulating chalazion. Adenoid cystic carcinoma in the eyelid may have a more favorable prognosis than that in the lacrimal gland. Copyright (c) Japanese Ophthalmological Society 2006.
BACKGROUND:Primary cutaneous adenoid cystic carcinoma is one of the rarest eyelid tumors. CASE: A 39-year-old man presented with a small subcutaneous induration in his left lower eyelid close to the lower lacrimal punctum. OBSERVATIONS: Under a clinical diagnosis of chalazion, the eyelid induration was extracted surgically via the palpebral conjunctiva. Histopathological examination of the extracted tumor revealed proliferation of basaloid cells with a prominent cribriform pattern containing Alcian blue-positive and periodic acid Schiff-positive material, leading to a diagnosis of adenoid cystic carcinoma. The patient subsequently underwent extended radical excision including the lacrimal sac. No recurrence was observed during 20 months after surgery. CONCLUSIONS:Adenoid cystic carcinoma should be considered as a differential diagnosis of eyelid tumors simulating chalazion. Adenoid cystic carcinoma in the eyelid may have a more favorable prognosis than that in the lacrimal gland. Copyright (c) Japanese Ophthalmological Society 2006.