Literature DB >> 1689710

Antibacterial properties of the bicyclic pyrazolidinones.

N E Allen1, J N Hobbs, D A Preston, J R Turner, C Y Wu.   

Abstract

LY173013 and LY186826 are bicyclic pyrazolidinones containing a novel aza-gamma-lactam ring structure. The antibacterial properties of these compounds appear to be related to those of beta-lactam antibiotics in that both classes of compounds share certain common binding molecules such as beta-lactamases and penicillin-binding proteins.

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Year:  1990        PMID： 1689710     DOI： 10.7164/antibiotics.43.92

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  3 in total

1.  Electrostatic and structural similarity of classical and non-classical lactam compounds.

Authors:  M Coll; J Frau; B Vilanova; J Donoso; F Muñoz
Journal:  J Comput Aided Mol Des       Date:  2001-09       Impact factor: 3.686

2.  A γ-Lactam Siderophore Antibiotic Effective against Multidrug-Resistant Gram-Negative Bacilli.

Authors:  Joel A Goldberg; Ha Nguyen; Vijay Kumar; Elizabeth J Spencer; Denton Hoyer; Emma K Marshall; Anna Cmolik; Margaret O'Shea; Steven H Marshall; Andrea M Hujer; Kristine M Hujer; Susan D Rudin; T Nicholas Domitrovic; Christopher R Bethel; Krisztina M Papp-Wallace; Latania K Logan; Federico Perez; Michael R Jacobs; David van Duin; Barry M Kreiswirth; Robert A Bonomo; Mark S Plummer; Focco van den Akker
Journal:  J Med Chem       Date:  2020-06-02       Impact factor: 7.446

Review 3.  Development of new drugs for an old target: the penicillin binding proteins.

Authors:  Astrid Zervosen; Eric Sauvage; Jean-Marie Frère; Paulette Charlier; André Luxen
Journal:  Molecules       Date:  2012-10-24       Impact factor: 4.411
  3 in total

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