Literature DB >> 16896294

Unloading joints to treat osteoarthritis, including joint distraction.

Floris P J G Lafeber1, Femke Intema, Peter M Van Roermund, Anne C A Marijnissen.   

Abstract

PURPOSE OF REVIEW: Patients are increasingly becoming interested in nonpharmacologic approaches to manage their osteoarthritis. This review examines the recent literature on the potential beneficial effects of unloading joints in the treatment of osteoarthritis, with a focus on joint distraction. RECENT
FINDINGS: Mechanical factors are involved in the development and progression of osteoarthritis. If "loading" is a major cause in development and progression of osteoarthritis, then "unloading" may be able to prevent progression. There is evidence that unloading may be effective in reducing pain and slowing down structural damage. This review describes unloading by footwear and bracing (nonsurgical), unloading by osteotomy (surgical), and has a focus on unloading by joint distraction. Excellent reviews in all these three fields have been published over the past few years. Recent studies argue for the usefulness of a biomechanical approach to improve function and possibly reduce disease progression in osteoarthritis.
SUMMARY: To improve patient function and possibly reduce disease progression, a biomechanical approach should be considered in treating patients with osteoarthritis. Further research (appropriate high-quality clinical trials) and analysis (clinical as well as preclinical and fundamental) are still necessary, however, to understand, validate, and refine the different approaches of unloading to treat osteoarthritis.

Entities:  

Mesh:

Year:  2006        PMID: 16896294     DOI: 10.1097/01.bor.0000240366.54960.a1

Source DB:  PubMed          Journal:  Curr Opin Rheumatol        ISSN: 1040-8711            Impact factor:   5.006


  20 in total

1.  Five-Year Follow-up of Knee Joint Distraction: Clinical Benefit and Cartilaginous Tissue Repair in an Open Uncontrolled Prospective Study.

Authors:  Jan-Ton A D van der Woude; Karen Wiegant; Peter M van Roermund; Femke Intema; Roel J H Custers; Felix Eckstein; Jaap M van Laar; Simon C Mastbergen; Floris P J G Lafeber
Journal:  Cartilage       Date:  2016-08-26       Impact factor: 4.634

2.  Low-intensity pulsed ultrasound (LIPUS) and pulsed electromagnetic field (PEMF) treatments affect degeneration of cultured articular cartilage explants.

Authors:  Lijun Tan; Yijin Ren; Theo G van Kooten; Dirk W Grijpma; Roel Kuijer
Journal:  Int Orthop       Date:  2014-09-30       Impact factor: 3.075

3.  Surgical interventions for symptomatic mild to moderate knee osteoarthritis.

Authors:  Jonathan S Palmer; A Paul Monk; Sally Hopewell; Lee E Bayliss; William Jackson; David J Beard; Andrew J Price
Journal:  Cochrane Database Syst Rev       Date:  2019-07-19

Review 4.  Cartilage regeneration for treatment of osteoarthritis: a paradigm for nonsurgical intervention.

Authors:  Moti L Tiku; Hatem E Sabaawy
Journal:  Ther Adv Musculoskelet Dis       Date:  2015-06       Impact factor: 5.346

Review 5.  Unload it: the key to the treatment of knee osteoarthritis.

Authors:  Craig Waller; David Hayes; Jon E Block; Nicholas J London
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-02-05       Impact factor: 4.342

6.  Post-traumatic osteoarthritis progression is diminished by early mechanical unloading and anti-inflammatory treatment in mice.

Authors:  A W Hsia; E H Jbeily; M E Mendez; H C Cunningham; K K Biris; H Bang; C A Lee; G G Loots; B A Christiansen
Journal:  Osteoarthritis Cartilage       Date:  2021-10-13       Impact factor: 6.576

7.  A phenotypically restricted set of primary afferent nerve fibers innervate the bone versus skin: therapeutic opportunity for treating skeletal pain.

Authors:  Juan Miguel Jimenez-Andrade; William G Mantyh; Aaron P Bloom; Haili Xu; Alice S Ferng; Gregory Dussor; Todd W Vanderah; Patrick W Mantyh
Journal:  Bone       Date:  2009-09-18       Impact factor: 4.398

8.  Chronic in vivo load alteration induces degenerative changes in the rat tibiofemoral joint.

Authors:  M L Roemhildt; B D Beynnon; A E Gauthier; M Gardner-Morse; F Ertem; G J Badger
Journal:  Osteoarthritis Cartilage       Date:  2012-11-01       Impact factor: 6.576

Review 9.  Functional articular cartilage repair: here, near, or is the best approach not yet clear?

Authors:  Simon C Mastbergen; Daniël B F Saris; Floris P J G Lafeber
Journal:  Nat Rev Rheumatol       Date:  2013-03-19       Impact factor: 20.543

10.  Innovative application of Cox Flexion Distraction Decompression to the knee: a retrospective case series.

Authors:  Luigi Albano
Journal:  J Can Chiropr Assoc       Date:  2017-08
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