| Literature DB >> 1689570 |
A B Wennerberg1, R M Cooke, M Carlquist, R Rigler, I D Campbell.
Abstract
The conformations of the neuropeptide galanin in water and trifluoroethanol solutions have been examined by 1H NMR spectroscopy. Analysis of two-dimensional NMR experiments enabled the assignment of virtually all the 1H resonances of galanin in trifluoroethanol solution and many of the 1H resonances in aqueous solution. Interpretation of the NMR data in structural terms suggests that in trifluoroethanol galanin is predominantly helical while in water it does not adopt a fixed conformation.Entities:
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Year: 1990 PMID： 1689570 DOI： 10.1016/0006-291x(90)90980-2
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575