Literature DB >> 16895668

[Renin-secreting tumour: about a new diagnosed case during pregnancy].

Francis Ducret1, Cécile Turc-Baron, Philippe Pointet, Guillaume Vernin, Olivier Skowron, Brigitte Mc Gregor, Jean-Marie Gasc, Gaspard Beaune, Madeleine Vincent.   

Abstract

A 29 year-old female patient developed severe arterial hypertension in the beginning of her second pregnancy. Investigations performed at 16 weeks of amenorrhea showed hypokaliemia in relation to severe hyperreninism: plasma active renin was 25 fold normal value, 94% as prorenin (prorenin representing 94% of total renin). Radiological investigations including ultrasonography and MRI disclosed an homogenous and avascular tumor in the right kidney. Its ablation confirmed renin tumor, and allowed recovery from HTA and continuation of pregnancy. This is the 75th reported case in the literature, enabling to make a new statement about diagnostic and therapeutic procedures, which are modified during pregnancy by contra-indication to X-rays and renin-angiotensin-aldosteron axis inhibitors.

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Year:  2005        PMID: 16895668     DOI: 10.1016/j.nephro.2005.01.008

Source DB:  PubMed          Journal:  Nephrol Ther        ISSN: 1769-7255            Impact factor:   0.722


  2 in total

1.  Severe hypertension and encephalopathy due to Renin-producing hepatoblastoma.

Authors:  Azita Tavasoli; Mitra Mehrazma; Nakisa Hooman; Ladan Afshar Khas
Journal:  Iran J Cancer Prev       Date:  2013

2.  Specific targeting of caspase-9/PP2A interaction as potential new anti-cancer therapy.

Authors:  Issam Arrouss; Fariba Nemati; Fernando Roncal; Marie Wislez; Karim Dorgham; David Vallerand; Nathalie Rabbe; Narjesse Karboul; Françoise Carlotti; Jeronimo Bravo; Dominique Mazier; Didier Decaudin; Angelita Rebollo
Journal:  PLoS One       Date:  2013-04-23       Impact factor: 3.240

  2 in total

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