| Literature DB >> 16894963 |
Maribel Pacheco-Sanchez1, Yvan Boutin, Paul Angers, André Gosselin, Russell J Tweddell.
Abstract
Polysaccharides from higher Basidiomycete mushrooms, mainly beta-D-glucans, are considered to be potent bioactive fungal compounds. In this study a beta-glucan (1.237 x 10(6) Da) consisting of (1-->3) and (1-->4) glucosidic linkages, named Collybia dryophila polysaccharide (CDP), was extracted from the wild mushroom C. dryophila. CDP was shown to strongly inhibit nitric oxide production in activated macrophages suggesting that this polysaccharide displays a potential anti-inflammatory activity. In addition it was shown that polysaccharides similar to CDP (CDP-like) are present in Lentinus edodes and different wild mushrooms collected in northeastern North America.Entities:
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Year: 2006 PMID: 16894963 DOI: 10.3852/mycologia.98.2.180
Source DB: PubMed Journal: Mycologia ISSN: 0027-5514 Impact factor: 2.696