| Literature DB >> 1689479 |
R Landesberg1, M Fallon, R Insel.
Abstract
The peripheral blood lymphocytes of patients with recurrent aphthous ulcers (RAU) were studied during various stages of their disease by two-color immunofluorescence with the use of monoclonal antibodies directed against human T cells (CD3), T helper cells (CD4), T suppressor cells (CD8), T helper/inducer cells (CDw29), and T suppressor/inducer cells (CD45R). All patients with severe RAU showed increased numbers of T helper/inducer cells (CDw29) and decreased numbers of T suppressor/inducer cells (CD45R). One of six patients with RAU showed a decreased T helper/T suppressor ratio (CD4/CD8). These findings suggest that patients with RAU may possess primary immunologic abnormalities.Entities:
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Year: 1990 PMID： 1689479 DOI： 10.1016/0030-4220(90)90329-q
Source DB: PubMed Journal: Oral Surg Oral Med Oral Pathol ISSN： 0030-4220