Literature DB >> 1689449

Rat gastric histamine release: a sensitive gastrin bioassay.

A K Sandvik1, H L Waldum.   

Abstract

Acid secretion and histamine release from the totally isolated vascularly perfused rat stomach are sensitive parameters for the biological effects of gastrin. By optimalizing the Ca2+ concentration of the vascular perfusate the sensitivity for stimulation of acid secretion was improved from 65 to 16 pmol/l gastrin 1-17 (G-17). Measurement of venous histamine before and after gastrin in each stomach preparation excluded inter-stomach variability and improved the sensitivity to 2 pmol/l G-17. This is the most sensitive gastrin bioassay reported, with a detection limit comparable to that of radioimmunoassay.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 1689449     DOI： 10.1016/0024-3205(90)90089-a

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


  6 in total

Review 1.  Gastrin-histamine sequence in the regulation of gastric acid secretion.

Authors:  H L Waldum; A K Sandvik; E Brenna; H Petersen
Journal:  Gut       Date:  1991-06       Impact factor: 23.059

2.  YM022, a potent and selective gastrin/CCK-B receptor antagonist, inhibits peptone meal-induced gastric acid secretion in Heidenhain pouch dogs.

Authors:  H Yuki; A Nishida; A Miyake; H Ito; S Akuzawa; Y Takinami; Y Takemoto; K Miyata
Journal:  Dig Dis Sci       Date:  1997-04       Impact factor: 3.199

Review 3.  Gastrin May Mediate the Carcinogenic Effect of Helicobacter pylori Infection of the Stomach.

Authors:  Helge L Waldum; Øyvind Hauso; Øystein F Sørdal; Reidar Fossmark
Journal:  Dig Dis Sci       Date:  2014-12-06       Impact factor: 3.199

4.  Trophic effect of gastrin on the enterochromaffin like cells of the rat stomach: establishment of a dose response relationship.

Authors:  E Brenna; H L Waldum
Journal:  Gut       Date:  1992-10       Impact factor: 23.059

Review 5.  Helicobacter pylori and gastric acid: an intimate and reciprocal relationship.

Authors:  Helge L Waldum; Per M Kleveland; Øystein F Sørdal
Journal:  Therap Adv Gastroenterol       Date:  2016-08-23       Impact factor: 4.409

Review 6.  Not only stem cells, but also mature cells, particularly neuroendocrine cells, may develop into tumours: time for a paradigm shift.

Authors:  Helge L Waldum; Kjell Öberg; Øystein F Sørdal; Arne K Sandvik; Bjørn I Gustafsson; Patricia Mjønes; Reidar Fossmark
Journal:  Therap Adv Gastroenterol       Date:  2018-05-27       Impact factor: 4.409
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.