Literature DB >> 1689322

A semiautomated method for measuring brain infarct volume.

R A Swanson1, M T Morton, G Tsao-Wu, R A Savalos, C Davidson, F R Sharp.   

Abstract

An accurate, reproducible method for determining the infarct volumes of gray matter structures is presented for use with presently available image analysis systems. Areas of stained sections with optical densities above that of a threshold value are automatically recognized and measured. This eliminates the potential error and bias inherent in manually delineating infarcted regions. Moreover, the volume of surviving normal gray matter is determined rather than that of the infarct. This approach minimizes the error that is introduced by edema, which distorts and enlarges the infarcted tissue and surrounding white matter.

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Year:  1990        PMID: 1689322     DOI: 10.1038/jcbfm.1990.47

Source DB:  PubMed          Journal:  J Cereb Blood Flow Metab        ISSN: 0271-678X            Impact factor:   6.200


  517 in total

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4.  Molecular adaptations in vasoactive systems during acute stroke in salt-induced hypertension.

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10.  Delayed administration of interleukin-1 receptor antagonist protects against transient cerebral ischaemia in the rat.

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Journal:  Br J Pharmacol       Date:  2003-08-26       Impact factor: 8.739

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