Literature DB >> 16892778

Dose counting and the use of pressurized metered-dose inhalers: running on empty.

Nancy Sander1, Sandra J Fusco-Walkert, Julia M Harder, Bradley E Chipps.   

Abstract

BACKGROUND: Pressurized metered-dose inhalers (pMDIs) are the cornerstone of asthma treatment. The pMDI is an economic and portable medication delivery system, but the device does not indicate how much medicine remains in the canister once a patient starts using it.
OBJECTIVE: To determine how patients evaluate the contents of their pMDI and whether they are either discarding inhalers when medication remains or using inhalers beyond the indicated number of doses.
METHODS: This study was conducted in April 2003 via a 6.5-minute telephone interview with a random sample of 500 families with asthma from across the United States.
RESULTS: Of the 500 respondents participating in the telephone interview, nearly one third (31.6%) named an inhaled corticosteroid or bronchodilator and inhaled corticosteroid combination as the inhaler used when wheezing, coughing, or short of breath. Respondents using a bronchodilator (n = 342) varied in the frequency with which they use their pMDIs: 31.9% daily, 18.7% weekly, 23.4% monthly, and 23.1% less than once per month. More than half (53.8%) of bronchodilator users refill their prescriptions more frequently than recommended by national guidelines. Only 36% of bronchodilator users reported ever having been told to keep track of pMDI doses used. Of those, 79% had been advised to do so by a physician, 6% by a pharmacist, and 3% by a nurse. Eighty-seven (25%) of the 342 respondents who named a bronchodilator reported having found their pMDI empty during an asthma exacerbation. Seven of those patients had to call 911. Of these 87 patients, 71 (82%) considered their pMDI empty when absolutely nothing came out.
CONCLUSIONS: Patients do not have a reliable means of monitoring the contents of their metered-dose inhalers, which is causing serious problems that need to be addressed. Given the necessity of a reliable dose counting method, it is clear that manufacturers should include dose counters as a standard feature of every metered-dose inhaler.

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Year:  2006        PMID: 16892778     DOI: 10.1016/s1081-1206(10)61366-x

Source DB:  PubMed          Journal:  Ann Allergy Asthma Immunol        ISSN: 1081-1206            Impact factor:   6.347


  8 in total

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2.  Emergency department visits for acute asthma by adults who ran out of their inhaled medications.

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Review 4.  Improving asthma management: the case for mandatory inclusion of dose counters on all rescue bronchodilators.

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5.  The Effect of Training Inhalation Technique with or without Spacer on Maximum Expiratory Flow Rate and Inhaler Usage Skills in Asthmatic Patients: A Randomized Controlled Trial.

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Review 7.  Inhaler technique: facts and fantasies. A view from the Aerosol Drug Management Improvement Team (ADMIT).

Authors:  Mark L Levy; P N R Dekhuijzen; P J Barnes; M Broeders; C J Corrigan; B L Chawes; L Corbetta; J C Dubus; Th Hausen; F Lavorini; N Roche; J Sanchis; Omar S Usmani; J Viejo; W Vincken; Th Voshaar; G K Crompton; Soren Pedersen
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Review 8.  Climate change in healthcare: Exploring the potential role of inhaler prescribing.

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  8 in total

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