Literature DB >> 16892645

Triamcinolone-induced intraocular pressure elevation: intravitreal injection for macular edema and posterior subtenon injection for uveitis.

Seung Youn Jea1, Ik Soo Byon, Boo Sup Oum.   

Abstract

PURPOSE: To assess the effect of intravitreal and posterior subtenon injections of triamcinolone acetonide (TA) on intraocular pressure (IOP).
METHODS: we reviewed 42 consecutive eyes after intravitreal TA injection (IVTA) and 43 eyes following posterior subtenon TA injection (PSTA). All cases had a minimum follow-up time of three months. After injection, the value and time of the maximal IOP, the amount of IOP elevation and the needs of the medication were assessed.
RESULTS: The lOP increased significantly (p < 0.001) from 16.3 +/- 2.5 mmHg preoperatively to a mean maximum of 21.7 +/- 5.3 mmHg in the IVTA group, and from 15.3 +/- 4.5 mmHg to 20.6 +/- 3.0 mmHg in the PSTA group. An elevation in the IOP of more than 5 mmHg from the baseline lOP was seen in 52.4% of the IVTA group at a mean time of 3.1 weeks postoperatively, and 44.2% of the PSTA group displayed an IOP elevation at 5.9 weeks.
CONCLUSIONS: Both developed significant elevations of IOP, but this appeared at a later date in the PSTA group. Careful follow-up after local injection of steroids is necessary.

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Year:  2006        PMID: 16892645      PMCID: PMC2908835          DOI: 10.3341/kjo.2006.20.2.99

Source DB:  PubMed          Journal:  Korean J Ophthalmol        ISSN: 1011-8942


  20 in total

1.  Intravitreal triamcinolone acetonide in exudative age-related macular degeneration.

Authors:  R P Danis; T A Ciulla; L M Pratt; W Anliker
Journal:  Retina       Date:  2000       Impact factor: 4.256

2.  Intraocular pressure after intravitreal injection of triamcinolone acetonide.

Authors:  J B Jonas; I Kreissig; R Degenring
Journal:  Br J Ophthalmol       Date:  2003-01       Impact factor: 4.638

3.  Secondary chronic open-angle glaucoma after intravitreal triamcinolone acetonide.

Authors:  Jost B Jonas; Ingrid Kreissig; Robert Degenring
Journal:  Arch Ophthalmol       Date:  2003-05

4.  Intraocular availability of triamcinolone acetonide after intravitreal injection.

Authors:  Jost B Jonas
Journal:  Am J Ophthalmol       Date:  2004-03       Impact factor: 5.258

5.  Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection.

Authors:  Paul M Beer; Sophie J Bakri; Ravinder J Singh; Weiguo Liu; George B Peters; Michael Miller
Journal:  Ophthalmology       Date:  2003-04       Impact factor: 12.079

6.  Intravitreal injection of crystalline cortisone as adjunctive treatment of proliferative diabetic retinopathy.

Authors:  J B Jonas; J K Hayler; A Söfker; S Panda-Jonas
Journal:  Am J Ophthalmol       Date:  2001-04       Impact factor: 5.258

7.  Intravitreal triamcinolone for uveitic cystoid macular edema: an optical coherence tomography study.

Authors:  R J Antcliff; D J Spalton; M R Stanford; E M Graham; T J ffytche; J Marshall
Journal:  Ophthalmology       Date:  2001-04       Impact factor: 12.079

8.  Intravitreal injection of crystalline cortisone as adjunctive treatment of proliferative vitreoretinopathy.

Authors:  J B Jonas; J K Hayler; S Panda-Jonas
Journal:  Br J Ophthalmol       Date:  2000-09       Impact factor: 4.638

9.  Safety of an intravitreal injection of triamcinolone: results from a randomized clinical trial.

Authors:  Mark C Gillies; Judy M Simpson; Frank A Billson; Wei Luo; Philip Penfold; William Chua; Paul Mitchell; Meidong Zhu; Alex B L Hunyor
Journal:  Arch Ophthalmol       Date:  2004-03

10.  The effect of intravitreal triamcinolone acetonide on intraocular pressure.

Authors:  Sophie J Bakri; Paul M Beer
Journal:  Ophthalmic Surg Lasers Imaging       Date:  2003 Sep-Oct
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  4 in total

1.  Uveitic Macular Edema: Treatment Update.

Authors:  Raquel Goldhardt; Bradley Simon Rosen
Journal:  Curr Ophthalmol Rep       Date:  2016-02-18

2.  Periocular corticosteroid injections in uveitis: effects and complications.

Authors:  H Nida Sen; Susan Vitale; Sapna S Gangaputra; Robert B Nussenblatt; Teresa L Liesegang; Grace A Levy-Clarke; James T Rosenbaum; Eric B Suhler; Jennifer E Thorne; C Stephen Foster; Douglas A Jabs; John H Kempen
Journal:  Ophthalmology       Date:  2014-07-11       Impact factor: 12.079

3.  Interventions for the treatment of uveitic macular edema: a systematic review and meta-analysis.

Authors:  Rushmia Karim; Evripidis Sykakis; Susan Lightman; Samantha Fraser-Bell
Journal:  Clin Ophthalmol       Date:  2013-06-11

Review 4.  Current intravitreal therapy and ocular hypertension: A review.

Authors:  Aditya Sudhalkar; Alper Bilgic; Shail Vasavada; Laurent Kodjikian; Thibaud Mathis; Fransesc March de Ribot; Thanos Papakostas; Viraj Vasavada; Vaishali Vasavada; Samaresh Srivastava; Deepak Bhojwani; Pooja Ghia; Anand Sudhalkar
Journal:  Indian J Ophthalmol       Date:  2021-02       Impact factor: 1.848

  4 in total

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