Literature DB >> 16892386

The nuclear receptor superfamily and drug discovery.

John T Moore1, Jon L Collins, Kenneth H Pearce.   

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Year:  2006        PMID： 16892386     DOI： 10.1002/cmdc.200600006

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


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  41 in total

1.  Cytotoxicity of 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione (DCPT) and analogues in wild type and CYP3A4 stably transfected HepG2 cells.

Authors:  Douglas M Frederick; Erina Y Jacinto; Niti N Patel; Thomas H Rushmore; Ruy Tchao; Peter J Harvison
Journal:  Toxicol In Vitro       Date:  2011-09-22       Impact factor: 3.500

2.  The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity.

Authors:  Natascha Hermann-Kleiter; Thomas Gruber; Christina Lutz-Nicoladoni; Nikolaus Thuille; Friedrich Fresser; Verena Labi; Natalia Schiefermeier; Marei Warnecke; Lukas Huber; Andreas Villunger; Gregor Eichele; Sandra Kaminski; Gottfried Baier
Journal:  Immunity       Date:  2008-08-15       Impact factor: 31.745

Review 3.  Allosteric pathways in nuclear receptors - Potential targets for drug design.

Authors:  Elias J Fernandez
Journal:  Pharmacol Ther       Date:  2017-10-31       Impact factor: 12.310

4.  Synthesis of small molecule inhibitors of the orphan nuclear receptor steroidogenic factor-1 (NR5A1) based on isoquinolinone scaffolds.

Authors:  Joshua Roth; Franck Madoux; Peter Hodder; William R Roush
Journal:  Bioorg Med Chem Lett       Date:  2008-03-14       Impact factor: 2.823

Review 5.  Nuclear receptor Rev-erbα: up, down, and all around.

Authors:  Logan J Everett; Mitchell A Lazar
Journal:  Trends Endocrinol Metab       Date:  2014-07-22       Impact factor: 12.015

6.  Molecular mechanisms of transcriptional control by Rev-erbα: An energetic foundation for reconciling structure and binding with biological function.

Authors:  Anaïs Vaissière; Sylvie Berger; Deborah Harrus; Catherine Dacquet; Albane Le Maire; Jean A Boutin; Gilles Ferry; Catherine A Royer
Journal:  Protein Sci       Date:  2015-06-11       Impact factor: 6.725

Review 7.  Nuclear receptors in neural stem/progenitor cell homeostasis.

Authors:  Dimitrios Gkikas; Matina Tsampoula; Panagiotis K Politis
Journal:  Cell Mol Life Sci       Date:  2017-06-21       Impact factor: 9.261

8.  Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPARγ Drug Pioglitazone.

Authors:  Sarah A Mosure; Jinsai Shang; Jerome Eberhardt; Richard Brust; Jie Zheng; Patrick R Griffin; Stefano Forli; Douglas J Kojetin
Journal:  J Med Chem       Date:  2019-02-07       Impact factor: 7.446

9.  Synthesis and structure-activity relationship studies of novel dihydropyridones as androgen receptor modulators.

Authors:  Antonella Pepe; Michael Pamment; Yeong Sang Kim; Sunmin Lee; Min-Jung Lee; Kristin Beebe; Anton Filikov; Len Neckers; Jane B Trepel; Sanjay V Malhotra
Journal:  J Med Chem       Date:  2013-10-30       Impact factor: 7.446

10.  Predicting drug-target interaction networks based on functional groups and biological features.

Authors:  Zhisong He; Jian Zhang; Xiao-He Shi; Le-Le Hu; Xiangyin Kong; Yu-Dong Cai; Kuo-Chen Chou
Journal:  PLoS One       Date:  2010-03-11       Impact factor: 3.240
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