Literature DB >> 16892348

Efforts toward the total synthesis of tubulysins: new hopes for a more effective targeted drug delivery to tumors.

Dario Neri1, Giacomo Fossati, Matteo Zanda.   

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Year:  2006        PMID： 16892348     DOI： 10.1002/cmdc.200500043

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


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  4 in total

1.  Chemotherapeutic evaluation of a synthetic tubulysin analogue-dendrimer conjugate in c26 tumor bearing mice.

Authors:  William C Floyd; Gopal K Datta; Shinichi Imamura; Heidi M Kieler-Ferguson; Katherine Jerger; Andrew W Patterson; Megan E Fox; Francis C Szoka; Jean M J Fréchet; Jonathan A Ellman
Journal:  ChemMedChem       Date:  2011-01-03       Impact factor: 3.466

2.  Total synthesis and biological evaluation of tubulysin U, tubulysin V, and their analogues.

Authors:  Ranganathan Balasubramanian; Bhooma Raghavan; Adrian Begaye; Dan L Sackett; Robert A Fecik
Journal:  J Med Chem       Date:  2009-01-22       Impact factor: 7.446

3.  Pretubulysin: from hypothetical biosynthetic intermediate to potential lead in tumor therapy.

Authors:  Jennifer Herrmann; Yasser A Elnakady; Romina M Wiedmann; Angelika Ullrich; Manfred Rohde; Uli Kazmaier; Angelika M Vollmar; Rolf Müller
Journal:  PLoS One       Date:  2012-05-17       Impact factor: 3.240

4.  Stereoselective access to tubuphenylalanine and tubuvaline: improved Mn-mediated radical additions and assembly of a tubulysin tetrapeptide analog.

Authors:  Gregory K Friestad; Koushik Banerjee; Jean-Charles Marié; Umesh Mali; Lei Yao
Journal:  J Antibiot (Tokyo)       Date:  2016-02-17       Impact factor: 2.649
  4 in total

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