Literature DB >> 16892135

Modeling low-coherence enhanced backscattering using Monte Carlo simulation.

Hariharan Subramanian1, Prabhakar Pradhan, Young L Kim, Yang Liu, Xu Li, Vadim Backman.   

Abstract

Constructive interference between coherent waves traveling time-reversed paths in a random medium gives rise to the enhancement of light scattering observed in directions close to backscattering. This phenomenon is known as enhanced backscattering (EBS). According to diffusion theory, the angular width of an EBS cone is proportional to the ratio of the wavelength of light lambda to the transport mean-free-path length l(s)* of a random medium. In biological media a large l(s)* approximately 0.5-2 mm >> lambda results in an extremely small (approximately 0.001 degrees ) angular width of the EBS cone, making the experimental observation of such narrow peaks difficult. Recently, the feasibility of observing EBS under low spatial coherence illumination (spatial coherence length Lsc << l(s)*) was demonstrated. Low spatial coherence behaves as a spatial filter rejecting longer path lengths and thus resulting in an increase of more than 100 times in the angular width of low coherence EBS (LEBS) cones. However, a conventional diffusion approximation-based model of EBS has not been able to explain such a dramatic increase in LEBS width. We present a photon random walk model of LEBS by using Monte Carlo simulation to elucidate the mechanism accounting for the unprecedented broadening of the LEBS peaks. Typically, the exit angles of the scattered photons are not considered in modeling EBS in the diffusion regime. We show that small exit angles are highly sensitive to low-order scattering, which is crucial for accurate modeling of LEBS. Our results show that the predictions of the model are in excellent agreement with the experimental data.

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Year:  2006        PMID: 16892135     DOI: 10.1364/ao.45.006292

Source DB:  PubMed          Journal:  Appl Opt        ISSN: 1559-128X            Impact factor:   1.980


  4 in total

1.  Multiple scattering model for the penetration depth of low-coherence enhanced backscattering.

Authors:  Vladimir Turzhitsky; Nikhil N Mutyal; Andrew J Radosevich; Vadim Backman
Journal:  J Biomed Opt       Date:  2011-09       Impact factor: 3.170

2.  Characterization of light transport in scattering media at sub-diffusion length scales with Low-coherence Enhanced Backscattering.

Authors:  Vladimir Turzhitsky; Jeremy D Rogers; Nikhil N Mutyal; Hemant K Roy; Vadim Backman
Journal:  IEEE J Sel Top Quantum Electron       Date:  2010       Impact factor: 4.544

3.  Measurement of optical scattering properties with low-coherence enhanced backscattering spectroscopy.

Authors:  Vladimir Turzhitsky; Andrew J Radosevich; Jeremy D Rogers; Nikhil N Mutyal; Vadim Backman
Journal:  J Biomed Opt       Date:  2011-06       Impact factor: 3.170

4.  Quantitative imaging of scattering changes associated with epithelial proliferation, necrosis, and fibrosis in tumors using microsampling reflectance spectroscopy.

Authors:  Venkataramanan Krishnaswamy; P Jack Hoopes; Kimberley S Samkoe; Julia A O'Hara; Tayyaba Hasan; Brian W Pogue
Journal:  J Biomed Opt       Date:  2009 Jan-Feb       Impact factor: 3.170

  4 in total

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