Literature DB >> 16891603

Are adult offspring reliable informants about parental PTSD? A validation study.

Rachel Yehuda1, Ellen Labinsky, Lisa Tischler, Sarah R Brand, Yonit Lavin, William Blair, Linda M Bierer, Rachel Z Goodman, Robert A Grossman.   

Abstract

We developed a short questionnaire--Parental PTSD Questionnaire--(PPQ), designed to assess the presence of posttraumatic stress disorder (PTSD) symptoms in parents. Fifty-eight adult offspring of Holocaust survivors (23 men and 35 women) completed the questionnaire about a parent who was independently evaluated by a trained clinician using the Clinician Administered PTSD Scale (CAPS). Only 5.2% of the offspring reported, "not knowing" if their parent had experienced 10 or fewer symptoms, while 56.9% provided estimates for all 17 items. There were no significant differences between lifetime frequencies of the individual symptoms as endorsed on the PPQ compared to the CAPS when subjects with completed PPQs were compared with CAPS. Interrater reliability between offspring and clinician was highly significant for each of the items when evaluated separately so as to include data for subjects who endorsed not knowing if a certain symptom had been present. Further studies are warranted to examine the psychometric properties of this measure.

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Year:  2006        PMID: 16891603     DOI: 10.1196/annals.1364.047

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN: 0077-8923            Impact factor:   5.691


  7 in total

1.  Maternal PTSD associates with greater glucocorticoid sensitivity in offspring of Holocaust survivors.

Authors:  Amy Lehrner; Linda M Bierer; Vincent Passarelli; Laura C Pratchett; Janine D Flory; Heather N Bader; Iris R Harris; Aarti Bedi; Nikolaos P Daskalakis; Iouri Makotkine; Rachel Yehuda
Journal:  Psychoneuroendocrinology       Date:  2013-12-01       Impact factor: 4.905

2.  Maternal, not paternal, PTSD is related to increased risk for PTSD in offspring of Holocaust survivors.

Authors:  Rachel Yehuda; Amanda Bell; Linda M Bierer; James Schmeidler
Journal:  J Psychiatr Res       Date:  2008-02-20       Impact factor: 4.791

3.  Influences of maternal and paternal PTSD on epigenetic regulation of the glucocorticoid receptor gene in Holocaust survivor offspring.

Authors:  Rachel Yehuda; Nikolaos P Daskalakis; Amy Lehrner; Frank Desarnaud; Heather N Bader; Iouri Makotkine; Janine D Flory; Linda M Bierer; Michael J Meaney
Journal:  Am J Psychiatry       Date:  2014-08       Impact factor: 18.112

4.  Parental Post-traumatic Stress Disorder Symptoms Are Related to Successful Aging in Offspring of Holocaust Survivors.

Authors:  Amit Shrira; Liat Ayalon; Moshe Bensimon; Ehud Bodner; Tova Rosenbloom; Gal Yadid
Journal:  Front Psychol       Date:  2017-06-29

5.  Elevation of 11β-hydroxysteroid dehydrogenase type 2 activity in Holocaust survivor offspring: evidence for an intergenerational effect of maternal trauma exposure.

Authors:  Linda M Bierer; Heather N Bader; Nikolaos P Daskalakis; Amy L Lehrner; Iouri Makotkine; Jonathan R Seckl; Rachel Yehuda
Journal:  Psychoneuroendocrinology       Date:  2014-06-07       Impact factor: 4.905

6.  Maternal Age at Holocaust Exposure and Maternal PTSD Independently Influence Urinary Cortisol Levels in Adult Offspring.

Authors:  Heather N Bader; Linda M Bierer; Amy Lehrner; Iouri Makotkine; Nikolaos P Daskalakis; Rachel Yehuda
Journal:  Front Endocrinol (Lausanne)       Date:  2014-07-04       Impact factor: 5.555

7.  Intergenerational trauma is associated with expression alterations in glucocorticoid- and immune-related genes.

Authors:  Changxin Xu; Heather N Bader; Chris Chatzinakos; Nikolaos P Daskalakis; Peter Weber; Iouri Makotkine; Amy Lehrner; Linda M Bierer; Elisabeth B Binder; Rachel Yehuda
Journal:  Neuropsychopharmacology       Date:  2020-11-10       Impact factor: 7.853

  7 in total

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