Literature DB >> 16890515

IKK epsilon signaling: not just NF-kappaB.

Andreas Bergmann1.   

Abstract

IkappaB kinases (IKKs) are key components of NF-kappaB signaling pathways in innate immunity and inflammation. Surprisingly, three recent reports implicate IKKs in Drosophila in seemingly unrelated functions, including non-apoptotic caspase activation and cytoskeleton organization.

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Year:  2006        PMID: 16890515      PMCID: PMC2601670          DOI: 10.1016/j.cub.2006.07.010

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  19 in total

Review 1.  NF-kappaB signaling pathways in mammalian and insect innate immunity.

Authors:  N Silverman; T Maniatis
Journal:  Genes Dev       Date:  2001-09-15       Impact factor: 11.361

2.  A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity.

Authors:  N Silverman; R Zhou; S Stöven; N Pandey; D Hultmark; T Maniatis
Journal:  Genes Dev       Date:  2000-10-01       Impact factor: 11.361

3.  Drosophila IKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs.

Authors:  Erina Kuranaga; Hirotaka Kanuka; Ayako Tonoki; Kiwamu Takemoto; Takeyasu Tomioka; Masatomo Kobayashi; Shigeo Hayashi; Masayuki Miura
Journal:  Cell       Date:  2006-08-03       Impact factor: 41.582

4.  IKK epsilon regulates F actin assembly and interacts with Drosophila IAP1 in cellular morphogenesis.

Authors:  Kenzi Oshima; Michiko Takeda; Erina Kuranaga; Ryu Ueda; Toshiro Aigaki; Masayuki Miura; Shigeo Hayashi
Journal:  Curr Biol       Date:  2006-08-08       Impact factor: 10.834

5.  Neural stem cell differentiation is dependent upon endogenous caspase 3 activity.

Authors:  Pasan Fernando; Steve Brunette; Lynn A Megeney
Journal:  FASEB J       Date:  2005-08-15       Impact factor: 5.191

6.  Caspase activity and a specific cytochrome C are required for sperm differentiation in Drosophila.

Authors:  Eli Arama; Julie Agapite; Hermann Steller
Journal:  Dev Cell       Date:  2003-05       Impact factor: 12.270

7.  Caspase-mediated processing of the Drosophila NF-kappaB factor Relish.

Authors:  Svenja Stoven; Neal Silverman; Anna Junell; Marika Hedengren-Olcott; Deniz Erturk; Ylva Engstrom; Tom Maniatis; Dan Hultmark
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-05       Impact factor: 11.205

8.  Drosophila Ik2, a member of the I kappa B kinase family, is required for mRNA localization during oogenesis.

Authors:  Risa S Shapiro; Kathryn V Anderson
Journal:  Development       Date:  2006-03-15       Impact factor: 6.868

9.  spn-F encodes a novel protein that affects oocyte patterning and bristle morphology in Drosophila.

Authors:  Uri Abdu; Dikla Bar; Trudi Schüpbach
Journal:  Development       Date:  2006-03-15       Impact factor: 6.868

10.  Separable and redundant regulatory determinants in Cactus mediate its dorsal group dependent degradation.

Authors:  N Q Fernandez; J Grosshans; J S Goltz; D Stein
Journal:  Development       Date:  2001-08       Impact factor: 6.868

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