Literature DB >> 16890428

14Beta-hydroxy-10-deacetylbaccatin III as a convenient, alternative substrate for the improved synthesis of methoxylated second-generation taxanes.

Luciano Barboni1, Guido Giarlo, Roberto Ballini, Gabriele Fontana.   

Abstract

This article describes a new, convenient, improved synthesis of the 2-debenzoyl-2-m-methoxybenzoyl-7-triethylsilyl-13-oxo-14beta-hydroxybaccatin III 1,14-carbonate, the key intermediate in the synthesis of two new second-generation antitumor taxanes.

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Year:  2006        PMID： 16890428     DOI： 10.1016/j.bmcl.2006.07.067

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells.

Authors:  Ahmed Malki; Mona Mohsen; Hassan Aziz; Ola Rizk; Omima Shaban; Mohamed El-Sayed; Zaki A Sherif; Hayam Ashour
Journal:  Molecules       Date:  2016-02-18       Impact factor: 4.411

2.  Synthesis, antifungal activity, and QSAR studies of 1,6-dihydropyrimidine derivatives.

Authors:  Chirag Rami; Laxmanbhai Patel; Chhaganbhai N Patel; Jayshree P Parmar
Journal:  J Pharm Bioallied Sci       Date:  2013-10
  2 in total

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