| Literature DB >> 16889940 |
Achilleas Attilakos1, Evangellos Papakonstantinou, Kleopatra Schulpis, Konstantinos Voudris, Eustathia Katsarou, Sotiria Mastroyianni, Anastasia Garoufi.
Abstract
Plasma total homocysteine (p-tHcy), serum folate (s-F), serum vitamin B-12 (s-B12) and plasma pyridoxal-5'-phosphate (p-PLP) were measured in epileptic children before and after a 20-week period of sodium valproate (group A, n=32) and carbamazepine (group B, n=20) monotherapy. P-tHcy significantly increased in both groups, s-F and s-B12 significantly increased in group A, while s-F and p-PLP significantly decreased in group B. Our study showed an early effect of antiepileptic drug treatment on homocysteine metabolism.Entities:
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Year: 2006 PMID： 16889940 DOI： 10.1016/j.eplepsyres.2006.06.015
Source DB: PubMed Journal: Epilepsy Res ISSN： 0920-1211 Impact factor: 3.045