Literature DB >> 16889916

Synthesis and properties of cordycepin intercalates of Mg-Al-nitrate layered double hydroxides.

Qin Zheng Yang1, Jing Yang, Chang Kai Zhang.   

Abstract

Layered double hydroxides (LDHs) were investigated as cordycepin delivery nanocarriers for the first time in this study. Negatively charged biomolecule-cordycepin was intercalated in the gallery spaces of [Mg-Al-NO(3)] as the charge-compensating species, which was confirmed by the results of XRD, FT-IR, TEM, CZE and electrophoretic mobility. Cell experiment suggested that the new bio-LDH nanohybrid could prevent cordycepin decomposition by adenosine deaminase. This new formulation could possibly be used as a novel form cordycepin intravenous injection.

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Year:  2006        PMID： 16889916     DOI： 10.1016/j.ijpharm.2006.06.037

Source DB:  PubMed          Journal:  Int J Pharm        ISSN： 0378-5173            Impact factor:   5.875


  3 in total

1.  The Effect of Single, Binary and Ternary Anions of Chloride, Carbonate and Phosphate on the Release of 2,4-Dichlorophenoxyacetate Intercalated into the Zn-Al-layered Double Hydroxide Nanohybrid.

Authors:  Mohd Zobir Hussein; Adila Mohamad Jaafar; Asmah Hj Yahaya; Zulkarnain Zainal
Journal:  Nanoscale Res Lett       Date:  2009-08-04       Impact factor: 4.703

2.  Preparation and controlled-release studies of a protocatechuic acid-magnesium/aluminum-layered double hydroxide nanocomposite.

Authors:  Farahnaz Barahuie; Mohd Zobir Hussein; Samer Hasan Hussein-Al-Ali; Palanisamy Arulselvan; Sharida Fakurazi; Zulkarnain Zainal
Journal:  Int J Nanomedicine       Date:  2013-05-20

3.  Development of drug delivery systems based on layered hydroxides for nanomedicine.

Authors:  Farahnaz Barahuie; Mohd Zobir Hussein; Sharida Fakurazi; Zulkarnain Zainal
Journal:  Int J Mol Sci       Date:  2014-05-05       Impact factor: 5.923
  3 in total

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