Literature DB >> 16889612

Relationships between the adverse effects of drugs and genetic polymorphism in genes encoding drug metabolizing enzymes.

John O Miners, Richard O Day.   

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Year:  2006        PMID： 16889612      PMCID： PMC2000727          DOI： 10.1111/j.1365-2125.2006.02737.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


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  8 in total

1.  Glucuronidation of the aspirin metabolite salicylic acid by expressed UDP-glucuronosyltransferases and human liver microsomes.

Authors:  Gwendolyn E Kuehl; Jeannette Bigler; John D Potter; Johanna W Lampe
Journal:  Drug Metab Dispos       Date:  2005-10-28       Impact factor: 3.922

2.  CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk.

Authors:  J Bigler; J Whitton; J W Lampe; L Fosdick; R M Bostick; J D Potter
Journal:  Cancer Res       Date:  2001-05-01       Impact factor: 12.701

3.  Polymorphisms in genes encoding acetylsalicylic acid metabolizing enzymes are unrelated to upper gastrointestinal health in cardiovascular patients on acetylsalicylic acid.

Authors:  Martijn G H van Oijen; Sylvie Huybers; Wilbert H M Peters; Joost P H Drenth; Robert J F Laheij; Freek W A Verheugt; Jan B M J Jansen
Journal:  Br J Clin Pharmacol       Date:  2005-12       Impact factor: 4.335

Review 4.  Pharmacokinetics of salicylate in man.

Authors:  G Levy
Journal:  Drug Metab Rev       Date:  1979       Impact factor: 4.518

Review 5.  Drug interactions involving aspirin (acetylsalicylic acid) and salicylic acid.

Authors:  J O Miners
Journal:  Clin Pharmacokinet       Date:  1989-11       Impact factor: 6.447

6.  No evidence that polymorphisms in CYP2C8, CYP2C9, UGT1A6, PPARdelta and PPARgamma act as modifiers of the protective effect of regular NSAID use on the risk of colorectal carcinoma.

Authors:  Louise E McGreavey; Faye Turner; Gillian Smith; Katherine Boylan; D Timothy Bishop; David Forman; C Roland Wolf; Jennifer H Barrett
Journal:  Pharmacogenet Genomics       Date:  2005-10       Impact factor: 2.089

7.  Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications.

Authors:  M Ciotti; A Marrone; C Potter; I S Owens
Journal:  Pharmacogenetics       Date:  1997-12

8.  The metabolism of aspirin in man: a population study.

Authors:  A J Hutt; J Caldwell; R L Smith
Journal:  Xenobiotica       Date:  1986-03       Impact factor: 1.908
  8 in total

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